2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one


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2474 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 1802
2 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 615
3 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 445
4 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PK3CD_HUMAN PIK3CD Homo sapiens 5293 775 205
5 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 155
6 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 132
7 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 121
8 insulin INS_HUMAN INS Homo sapiens 3630 7950 120
9 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 110
10 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 106
11 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma D3ZFJ0_RAT Pik3cg Rattus norvegicus 298947 215 87
12 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 85
13 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 78
14 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 77
15 glycogen synthase kinase 3 beta GSK3B_HUMAN GSK3B Homo sapiens 2932 1189 77
16 phosphoinositide-3-kinase regulatory subunit 1 P85A_MOUSE Pik3r1 Mus musculus 18708 315 65
17 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 57
18 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 56
19 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 56
20 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 56
21 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 55
22 glycogen synthase kinase 3 beta GSK3B_RAT Gsk3b Rattus norvegicus 84027 622 52
23 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 51
24 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 49
25 insulin-like growth factor 1 IGF1_RAT Igf1 Rattus norvegicus 24482 1018 48
26 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 45
27 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 44
28 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 44
29 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 43
30 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 43
31 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 43
32 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 43
33 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 42
34 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 42
35 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 41
36 nitric oxide synthase 3 NOS3_HUMAN NOS3 Homo sapiens 4846 1142 36
37 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 36
38 peptidase inhibitor 3 ELAF_HUMAN PI3 Homo sapiens 5266 260 35
39 BCL2, apoptosis regulator BCL2_RAT Bcl2 Rattus norvegicus 24224 1676 35
40 mechanistic target of rapamycin kinase MTOR_MOUSE Mtor Mus musculus 56717 1120 33
41 NFE2 like bZIP transcription factor 2 NF2L2_RAT Nfe2l2 Rattus norvegicus 83619 1416 32
42 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 32
43 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 31
44 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 31
45 mechanistic target of rapamycin kinase MTOR_RAT Mtor Rattus norvegicus 56718 809 30
46 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 30
47 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta PK3CB_RAT Pik3cb Rattus norvegicus 85243 102 30
48 insulin-like growth factor 1 IGF1_MOUSE Igf1 Mus musculus 16000 712 30
49 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 29
50 heme oxygenase 1 HMOX1_RAT Hmox1 Rattus norvegicus 24451 1212 29