| Protein Name | heme oxygenase 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24451 |
| Gene Symbol | Hmox1 |
| UniProt | P06762 (HMOX1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
1212
Total Number of Articles : 2209 |
Description |
heme oxygenase 1 |
| Gene Summary |
Enables several functions, including heme binding activity; heme oxygenase (decyclizing) activity; and phospholipase D activity. Involved in several processes, including intracellular signal transduction; negative regulation of apoptotic process; and regulation of gene expression. Located in several cellular components, including caveola; endoplasmic reticulum; and nucleolus. Used to study several diseases, including artery disease (multiple); cerebrovascular disease (multiple); hepatic vascular disease (multiple); limb ischemia; and sciatic neuropathy. Biomarker of several diseases, including Sjogren's syndrome; artery disease (multiple); brain disease (multiple); liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and type 2 diabetes mellitus. Orthologous to human HMOX1 (heme oxygenase 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |