| 1 |
33235618 | PI3K inhibition sensitizes EGFR wild-type NSCLC cell lines to erlotinib chemotherapy. | 2021 Jan |
1 |
| 2 |
31557635 | The effects and mechanisms of GM-CSF on endometrial regeneration. | 2020 Jan |
1 |
| 3 |
31974627 | CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway. | 2020 Feb |
1 |
| 4 |
31658358 | miR-365 inhibits duck myoblast proliferation by targeting IGF-I via PI3K/Akt pathway. | 2019 Nov 29 |
1 |
| 5 |
29478280 | The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling. | 2018 Dec |
1 |
| 6 |
29524402 | Ghrelin promotes human non-small cell lung cancer A549 cell proliferation through PI3K/Akt/mTOR/P70S6K and ERK signaling pathways. | 2018 Apr 6 |
1 |
| 7 |
30119206 | Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma. | 2018 Oct |
1 |
| 8 |
33052635 | Thioridazine upregulates programmed cell death 4 to induce apoptosis in nasopharyngeal carcinoma through the PI3K/Akt signalling pathway. | 2018 Feb |
1 |
| 9 |
26506538 | Microcystin-LR promotes proliferation by activating Akt/S6K1 pathway and disordering apoptosis and cell cycle associated proteins phosphorylation in HL7702 cells. | 2016 Jan 5 |
1 |
| 10 |
26994515 | Naringenin-induced migration of embrynoic trophectoderm cells is mediated via PI3K/AKT and ERK1/2 MAPK signaling cascades. | 2016 Jun 15 |
2 |
| 11 |
27167250 | The ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor-Mediated Proliferation of SNU-407 Colon Cancer Cells. | 2016 Dec |
2 |
| 12 |
25578563 | PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester. | 2015 Mar |
1 |
| 13 |
25903737 | Interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the PI3K/Akt/mTOR signaling pathway in hippocampal neurons. | 2015 May 15 |
1 |
| 14 |
26884863 | 17β-estradiol activates mTOR in chondrocytes by AKT-dependent and AKT-independent signaling pathways. | 2015 |
2 |
| 15 |
24030871 | Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation. | 2014 Jan |
1 |
| 16 |
24851866 | The cytoplasmic tail of FPC antagonizes the full-length protein in the regulation of mTOR pathway. | 2014 |
1 |
| 17 |
25146167 | Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, JAK/STAT and Notch-1 pathways, indicate their involvement in meningioma development. | 2014 Oct |
1 |
| 18 |
25486532 | Phosphorylation of ribosomal protein S6 kinase 1 at Thr421/Ser424 and dephosphorylation at Thr389 regulates SP600125-induced polyploidization of megakaryocytic cell lines. | 2014 |
1 |
| 19 |
23793038 | Activation of the PI3K-AKT-mTOR signaling pathway promotes DEHP-induced Hep3B cell proliferation. | 2013 Sep |
1 |
| 20 |
23275900 | PI3K/AKT/mTOR signaling pathway inhibitors in proliferation of retinal pigment epithelial cells. | 2012 |
1 |
| 21 |
21885991 | Signaling mechanisms mediating uridine adenosine tetraphosphate-induced proliferation of human vascular smooth muscle cells. | 2011 Dec |
1 |
| 22 |
21964931 | Ginsenoside-Rg1 mediates a hypoxia-independent upregulation of hypoxia-inducible factor-1α to promote angiogenesis. | 2011 Dec |
1 |
| 23 |
19889638 | Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway. | 2010 Jan 1 |
1 |
| 24 |
19074484 | mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors. | 2009 Feb |
1 |
| 25 |
19923913 | Targeting HER2 signaling pathway for radiosensitization: alternative strategy for therapeutic resistance. | 2009 Dec |
1 |
| 26 |
17971516 | TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK. | 2008 Feb |
1 |
| 27 |
18356276 | Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors. | 2008 Jul |
1 |
| 28 |
18622747 | Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines. | 2008 Jul |
1 |
| 29 |
16477012 | Synergistic roles of platelet-derived growth factor-BB and interleukin-1beta in phenotypic modulation of human aortic smooth muscle cells. | 2006 Feb 21 |
1 |
| 30 |
16717100 | Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways. | 2006 Jul 28 |
1 |
| 31 |
15501927 | Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation. | 2005 Feb |
1 |
| 32 |
15677443 | The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation. | 2005 Apr 8 |
1 |
| 33 |
15696050 | Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin. | 2005 Jan |
1 |
| 34 |
15715661 | Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells. | 2005 Mar |
1 |
| 35 |
16103079 | 15(S)-hydroxyeicosatetraenoic acid induces angiogenesis via activation of PI3K-Akt-mTOR-S6K1 signaling. | 2005 Aug 15 |
3 |
| 36 |
16139919 | Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells. | 2005 Dec |
1 |
| 37 |
15105162 | Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation. | 2004 Sep |
1 |
| 38 |
15208659 | L6 myoblast differentiation is modulated by Cdk5 via the PI3K-AKT-p70S6K signaling pathway. | 2004 Aug 12 |
3 |
| 39 |
15317677 | ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells. | 2004 Sep |
1 |
| 40 |
12668683 | Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland. | 2003 Jun 13 |
1 |
| 41 |
12681504 | Amino acid availability regulates S6K1 and protein synthesis in avian insulin-insensitive QM7 myoblasts. | 2003 Apr 10 |
1 |
| 42 |
12711332 | IL-10 synergistically enhances GM-CSF-induced CCR1 expression in myelomonocytic cells. | 2003 May 2 |
1 |
| 43 |
12907754 | Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways. | 2003 Nov |
1 |
| 44 |
12960228 | Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells. | 2003 Dec |
1 |
| 45 |
13679036 | Arachidonic acid activation of translation initiation signaling in vascular smooth muscle cells. | 2003 Oct 3 |
1 |
| 46 |
14516795 | Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase. | 2003 Oct 15 |
1 |
| 47 |
12171932 | N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A. | 2002 Oct 18 |
1 |
| 48 |
12225947 | Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation. | 2002 Oct |
2 |
| 49 |
12242656 | Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma. | 2002 Sep 26 |
3 |
| 50 |
12362981 | Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells. | 2002 |
1 |