2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

tumor necrosis factor ; Homo sapiens







77 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33613982 Low molecular weight-PAHs induced inflammation in A549 cells by activating PI3K/AKT and NF-κB signaling pathways. 2021 Jan 1
2 34052845 Autophagy inhibitors 3-MA and LY294002 repress osteoclastogenesis and titanium particle-stimulated osteolysis. 2021 Jul 13 1
3 34227646 Resveratrol prevents inflammation and oxidative stress response in LPS-induced human gingival fibroblasts by targeting the PI3K/AKT and Wnt/β-catenin signaling pathways. 2021 1
4 32112175 PI3K inhibitor treatment ameliorates the glucocorticoid insensitivity of PBMCs in severe asthma. 2020 Feb 28 1
5 30863067 Improving the anti-keloid outcomes through liposomes loading paclitaxel-cholesterol complexes. 2019 1
6 29427163 Anti-Inflammatory Effects of Hypophyllanthin and Niranthin Through Downregulation of NF-κB/MAPKs/PI3K-Akt Signaling Pathways. 2018 Jun 1
7 30090596 Amino-PAHs activated Nrf2/ARE anti-oxidative defense system and promoted inflammatory responses: the regulation of PI3K/Akt pathway. 2018 May 8 2
8 30348950 Azithromycin promotes alternatively activated macrophage phenotype in systematic lupus erythematosus via PI3K/Akt signaling pathway. 2018 Oct 22 1
9 30577658 Protective Effects of Total Saponins of Aralia elata (Miq.) on Endothelial Cell Injury Induced by TNF-α via Modulation of the PI3K/Akt and NF-κB Signalling Pathways. 2018 Dec 21 1
10 28371277 Overexpression of microRNA-138 alleviates human coronary artery endothelial cell injury and inflammatory response by inhibiting the PI3K/Akt/eNOS pathway. 2017 Aug 1
11 28633978 Airborne nitro-PAHs induce Nrf2/ARE defense system against oxidative stress and promote inflammatory process by activating PI3K/Akt pathway in A549 cells. 2017 Oct 1
12 24840719 Chemerin plays a protective role by regulating human umbilical vein endothelial cell-induced nitric oxide signaling in preeclampsia. 2015 Feb 1
13 25857968 Cordyceps sinensis polysaccharide inhibits PDGF-BB-induced inflammation and ROS production in human mesangial cells. 2015 Jul 10 1
14 26453509 Cucurbitacin E inhibits TNF-α-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-κB pathways. 2015 Dec 1
15 24441870 TNF-α induces cytosolic phospholipase A2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells. 2014 Mar 15 5
16 24487964 TNF-α induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways. 2014 Mar 1
17 24613819 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. 2014 Aug 1
18 24669186 Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. 2014 2
19 25168152 Tianeptine sodium salt suppresses TNF-α-induced expression of matrix metalloproteinase-9 in human carcinoma cells via suppression of the PI3K/Akt-mediated NF-κB pathway. 2014 Sep 1
20 23246833 27-hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages. 2013 Jan 11 2
21 23255946 Piceatannol inhibits MMP-9-dependent invasion of tumor necrosis factor-α-stimulated DU145 cells by suppressing the Akt-mediated nuclear factor-κB pathway. 2013 Jan 1
22 23328930 Resveratrol inhibits TNF-α-induced IL-1β, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway. 2013 Jul 2
23 21545687 Regulatory mechanisms of interleukin-8 production induced by tumour necrosis factor-α in human hepatocellular carcinoma cells. 2012 Mar 1
24 22437887 Caffeine induces endothelial tissue factor expression via phosphatidylinositol 3-kinase inhibition. 2012 May 1
25 22556157 Regulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinases. 2012 Oct 1
26 22707636 TNF-α induces epithelial-mesenchymal transition of renal cell carcinoma cells via a GSK3β-dependent mechanism. 2012 Aug 1
27 22820188 TNF-α promotes human retinal pigment epithelial (RPE) cell migration by inducing matrix metallopeptidase 9 (MMP-9) expression through activation of Akt/mTORC1 signaling. 2012 Aug 17 1
28 19859713 The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte. 2011 Jan 2
29 21075101 Tumor necrosis factor-α regulates p27 kip expression and apoptosis in smooth muscle cells of human carotid plaques via forkhead transcription factor O1. 2011 Feb 1
30 21152864 Interleukin-32α expression in human colonic subepithelial myofibroblasts. 2011 Feb 1
31 21354814 Cl-IB-MECA enhances TNF-α release in peritoneal macrophages stimulated with LPS. 2011 May 1
32 21904110 Induction of steroid sulfatase expression by tumor necrosis factor-α through phosphatidylinositol 3-kinase/Akt signaling pathway in PC-3 human prostate cancer cells. 2011 Nov 30 1
33 22026410 Inhibition of TNF-α-Induced Inflammation by andrographolide via down-regulation of the PI3K/Akt signaling pathway. 2011 Nov 28 1
34 19683795 Thrombin and activated protein C inhibit the expression of secretory group IIA phospholipase A(2) in the TNF-alpha-activated endothelial cells by EPCR and PAR-1 dependent mechanisms. 2010 Jan 2
35 20082310 FAK activation is required for TNF-alpha-induced IL-6 production in myoblasts. 2010 May 1
36 20139176 Inflammatory stimulation and hypoxia cooperatively activate HIF-1{alpha} in bronchial epithelial cells: involvement of PI3K and NF-{kappa}B. 2010 May 1
37 20333651 TNF-alpha induces matrix metalloproteinase-9 expression in A549 cells: role of TNFR1/TRAF2/PKCalpha-dependent signaling pathways. 2010 Aug 1
38 19217919 Intracellular signaling pathways involved in inhibition of PAI-1 expression by CNP in endothelial cells. 2009 Jun 5 1
39 19386602 Interleukin-32 expression in the pancreas. 2009 Jun 26 1
40 17971154 Tumour necrosis factor-alpha-mediated human polymeric immunoglobulin receptor expression is regulated by both mitogen-activated protein kinase and phosphatidylinositol-3-kinase in HT-29 cell line. 2008 Apr 1
41 17971516 TNF-alpha increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK. 2008 Feb 1
42 18239058 Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-32alpha induction in human pancreatic periacinar myofibroblasts. 2008 Mar 3
43 18468786 Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a. 2008 Sep 8 1
44 18483465 TNF alpha-induced down-regulation of estrogen receptor alpha in MCF-7 breast cancer cells. 2008 Sep 30 1
45 18632801 Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells. 2008 Oct 1
46 18690350 Adiponectin inhibits tissue factor expression and enhances tissue factor pathway inhibitor expression in human endothelial cells. 2008 Aug 2
47 16784840 Eicosapentaenoic acid inhibits TNF-alpha-induced Lnk expression in human umbilical vein endothelial cells: involvement of the PI3K/Akt pathway. 2007 Jan 1
48 17314215 Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. 2007 Jun 2
49 15703956 Inhibition of NF-kappaB renders human juvenile costal chondrocyte cell lines sensitive to TNF-alpha-mediated cell death. 2006 Jan 1
50 16051251 Statins prevent NF-kappaB transactivation independently of the IKK-pathway in human endothelial cells. 2006 Apr 1