2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

matrix metallopeptidase 9 ; Homo sapiens







56 Article(s)
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1 34052845 Autophagy inhibitors 3-MA and LY294002 repress osteoclastogenesis and titanium particle-stimulated osteolysis. 2021 Jul 13 2
2 31732769 Notch1 and PI3K/Akt signaling blockers DAPT and LY294002 coordinately inhibit metastasis of gastric cancer through mutual enhancement. 2020 Feb 1
3 32037484 Estradiol-Induced MMP-9 Expression via PELP1-Mediated Membrane-Initiated Signaling in ERα-Positive Breast Cancer Cells. 2020 Apr 2
4 32175411 Fentanyl inhibits the progression of gastric cancer through the suppression of MMP-9 via the PI3K/Akt signaling pathway. 2020 Feb 1
5 32431202 NLRC5 promotes cell migration and invasion by activating the PI3K/AKT signaling pathway in endometrial cancer. 2020 May 1
6 30074136 Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells. 2019 Feb 1
7 30668826 miR-188-5p regulates proliferation and invasion via PI3K/Akt/MMP-2/9 signaling in keloids. 2019 Feb 1 1
8 31502574 Calycosin down-regulates c-Met to suppress development of glioblastomas. 2019 Sep 1
9 25588050 Activation of G protein coupled estrogen receptor (GPER) promotes the migration of renal cell carcinoma via the PI3K/AKT/MMP-9 signals. 2018 Mar 4 1
10 29488612 Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells. 2018 May 2
11 29805303 Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT. 2018 1
12 30225216 Effects of LY294002 on the function of retinal endothelial cell in vitro. 2018 2
13 28288190 Tetrandrine inhibits migration and invasion of human renal cell carcinoma by regulating Akt/NF-κB/MMP-9 signaling. 2017 1
14 28344073 Role of thrombin-PAR1-PKCθ/δ axis in brain pericytes in thrombin-induced MMP-9 production and blood-brain barrier dysfunction in vitro. 2017 May 14 1
15 28844616 MicroRNA-21 promotes bone mesenchymal stem cells migration in vitro by activating PI3K/Akt/MMPs pathway. 2017 Dec 1
16 29296070 Fisetin inhibits epidermal growth factor-induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expression. 2017 1
17 29296214 NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway. 2017 Dec 8 1
18 31966870 CXCR4 enhances invasion and proliferation of bone marrow stem cells via PI3K/AKT/NF-κB signaling pathway. 2017 1
19 25784559 2,2',4,4'-Tetrabromodiphenyl ether promotes human neuroblastoma SH-SY5Y cells migration via the GPER/PI3K/Akt signal pathway. 2016 Feb 1
20 27125675 Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-κB Signaling Pathways. 2016 Jun 1
21 25266803 RNA interference-mediated knockdown of RhoGDI2 induces the migration and invasion of human lung cancer A549 cells via activating the PI3K/Akt pathway. 2015 Jan 1
22 25638174 Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer. 2015 Feb 1 1
23 25650742 Dibenzoylmethane, hydroxydibenzoylmethane and hydroxymethyldibenzoylmethane inhibit phorbol-12-myristate 13-acetate‑induced breast carcinoma cell invasion. 2015 Jun 1
24 26259977 HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation. 2015 Oct 1
25 24176823 Roles for GP IIb/IIIa and αvβ3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction. 2014 Mar 1 1
26 24816639 Knockdown of sphingosine kinase 1 inhibits the migration and invasion of human rheumatoid arthritis fibroblast-like synoviocytes by down-regulating the PI3K/AKT activation and MMP-2/9 production in vitro. 2014 Aug 2
27 25345853 Inhibitory effect of ethanol extract of Ocimum sanctum on osteopontin mediated metastasis of NCI-H460 non-small cell lung cancer cells. 2014 Oct 27 1
28 25382615 Extracts of Celastrus orbiculatus exhibit anti-proliferative and anti-invasive effects on human gastric adenocarcinoma cells. 2014 Nov 10 1
29 23229870 Resveratrol induces MMP-9 and cell migration via the p38 kinase and PI-3K pathways in HT1080 human fibrosarcoma cells. 2013 Feb 1
30 23255946 Piceatannol inhibits MMP-9-dependent invasion of tumor necrosis factor-α-stimulated DU145 cells by suppressing the Akt-mediated nuclear factor-κB pathway. 2013 Jan 1
31 24002703 Hypoxia induces connexin 43 dysregulation by modulating matrix metalloproteinases via MAPK signaling. 2013 Dec 2
32 22459175 PI3-K/Akt/JNK/NF-κB is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane. 2012 Jul 1
33 22820188 TNF-α promotes human retinal pigment epithelial (RPE) cell migration by inducing matrix metallopeptidase 9 (MMP-9) expression through activation of Akt/mTORC1 signaling. 2012 Aug 17 1
34 23326131 Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45. 2012 Dec 28 2
35 23461061 C-Myc overexpression promotes osteosarcoma cell invasion via activation of MEK-ERK pathway. 2012 1
36 27350769 LY294002 induces differentiation and inhibits invasion of glioblastoma cells by targeting GSK-3beta and MMP. 2012 1
37 21224998 The role of eIF5A in epidermal growth factor-induced proliferation of corneal epithelial cell association with PI3-k/Akt activation. 2011 Jan 6 1
38 21738655 Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes. 2011 1
39 19956873 Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells. 2010 Jan 1
40 20333651 TNF-alpha induces matrix metalloproteinase-9 expression in A549 cells: role of TNFR1/TRAF2/PKCalpha-dependent signaling pathways. 2010 Aug 1
41 20649564 IL-1beta induces expression of matrix metalloproteinase-9 and cell migration via a c-Src-dependent, growth factor receptor transactivation in A549 cells. 2010 Aug 1
42 19331685 Arachidonic acid increases matrix metalloproteinase 9 secretion and expression in human monocytic MonoMac 6 cells. 2009 Mar 30 1
43 19568240 Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion. 2009 Jul 21 1
44 19859997 Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice. 2009 Oct 28 1
45 21479382 Akt- and MAPK-mediated activation and secretion of MMP-9 into stroma in breast cancer cells upon heregulin treatment. 2008 Jan-Feb 1
46 16732316 Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway. 2006 Nov 9 1
47 16870179 Activation of toll-like receptor-9 induces matrix metalloproteinase-9 expression through Akt and tumor necrosis factor-alpha signaling. 2006 Aug 7 1
48 15800029 Production of matrix metalloproteinase-9 by activated human monocytes involves a phosphatidylinositol-3 kinase/Akt/IKKalpha/NF-kappaB pathway. 2005 Jul 1
49 16135959 Peptidoglycan of Staphylococcus aureus induces enhanced levels of matrix metalloproteinase-9 in human blood originating from neutrophils. 2005 Sep 1
50 16266864 Spontaneous and cytokine-evoked production of matrix metalloproteinases by bone marrow and peripheral blood pre-B cells in childhood acute lymphoblastic leukaemia. 2005 Sep 1