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33403593 | IGF-1 Alleviates Mitochondrial Apoptosis through the GSK3β/NF-κB/NLRP3 Signaling Pathway in LPS-Treated PC-12 Cells. | 2021 Jun |
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34632857 | Insulin-like growth factor reduced against decabromodiphenyl ether-209-induced neurodevelopmental toxicity in vivo and in vitro. | 2021 Dec |
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34717965 | The neuroprotective effects of Insulin-Like Growth Factor 1 via the Hippo/YAP signaling pathway are mediated by the PI3K/AKT cascade following cerebral ischemia/reperfusion injury. | 2021 Dec |
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30287160 | Insulin-like Growth Factor (IGF)-1 treatment stabilizes the microvascular cytoskeleton under ischemic conditions. | 2019 Jan |
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30066869 | Extracellular matrix promotes proliferation, migration and adhesion of airway smooth muscle cells in a rat model of chronic obstructive pulmonary disease via upregulation of the PI3K/AKT signaling pathway. | 2018 Sep |
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25136768 | Insulin-like growth factor-1 attenuates apoptosis and protects neurochemical phenotypes of dorsal root ganglion neurons with paclitaxel-induced neurotoxicity in vitro. | 2017 Feb |
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28210955 | The Effects of IGF-1 on TNF-α-Treated DRG Neurons by Modulating ATF3 and GAP-43 Expression via PI3K/Akt/S6K Signaling Pathway. | 2017 May |
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26743528 | Insulin-like Growth Factor 1 Regulates the Expression of ATP-Binding Cassette Transporter A1 in Pancreatic Beta Cells. | 2016 May |
2 |
| 9 |
24995704 | Involvement of two distinct signalling pathways in IGF-1-mediated central control of hypotensive effects in normotensive and hypertensive rats. | 2014 Sep |
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| 10 |
25474202 | IGF-1 promotes Brn-4 expression and neuronal differentiation of neural stem cells via the PI3K/Akt pathway. | 2014 |
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| 11 |
24049436 | IGF-1 protects retinal ganglion cells from hypoxia-induced apoptosis by activating the Erk-1/2 and Akt pathways. | 2013 |
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| 12 |
22490886 | Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells. | 2012 May 10 |
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| 13 |
22537549 | Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK-ERK pathways. | 2012 Aug |
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| 14 |
22575459 | Insulin-like growth factor-1 (IGF-1) inhibits the basolateral Cl channels in the thick ascending limb of the rat kidney. | 2012 Jul |
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22761619 | Effects of IGF-1 on I(K) and I(K1) Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes. | 2012 |
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| 16 |
20821260 | IGF-1 reduces BACE-1 expression in PC12 cells via activation of PI3-K/Akt and MAPK/ERK1/2 signaling pathways. | 2011 Jan |
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| 17 |
21311135 | Protective effects of IGF-1 on neurons under condition of hypoxia and the role of PI3K signal pathway. | 2011 Jan |
2 |
| 18 |
19411121 | Enhanced mesenchymal cell engraftment by IGF-1 improves left ventricular function in rats undergoing myocardial infarction. | 2010 Jan 7 |
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| 19 |
19060913 | Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway in FRTL thyroid cells. | 2009 Jan |
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| 20 |
18278798 | PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease. | 2008 Apr |
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| 21 |
18453753 | IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation. | 2008 |
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| 22 |
18671941 | Insulin-like growth factor-I inhibits rat arterial K(ATP) channels through pI 3-kinase. | 2008 Oct 3 |
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| 23 |
17382293 | Insulin-like growth factor 1 enhances the migratory capacity of mesenchymal stem cells. | 2007 May 11 |
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| 24 |
17556532 | Phosphatidylinositol 3-kinase/nuclear factor-kappa B signaling pathway is involved in the regulation of IGF-I on Fas-associated death domain-like interleukin-1-converting enzyme-inhibitory protein expression in cultured FRTL thyroid cells. | 2007 Jun |
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| 25 |
16911581 | The WT1 Wilms' tumor suppressor gene is a downstream target for insulin-like growth factor-I (IGF-I) action in PC12 cells. | 2006 Nov |
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15662223 | Vascular responses to IGF-I and insulin are impaired in aortae of hypertensive rats. | 2005 Feb |
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| 27 |
15845624 | Insulin-like growth factor (IGF)-I stimulates cell proliferation and induces IGF binding protein (IGFBP)-3 and IGFBP-5 gene expression in cultured growth plate chondrocytes via distinct signaling pathways. | 2005 Jul |
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| 28 |
16342423 | PKC alpha-dependent regulation of the IGF1 receptor in adult and embryonic rat cardiomyocytes. | 2005 Jul |
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15291750 | IGF-I inhibits apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway in pituitary cells. | 2004 Aug |
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| 30 |
12647306 | Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein-1 induction of alkaline phosphatase activity in fetal rat calvaria cells. | 2003 Apr 15 |
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| 31 |
12891709 | Forkhead transcription factor FoxO1 transduces insulin-like growth factor's signal to p27Kip1 in primary skeletal muscle satellite cells. | 2003 Sep |
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14625085 | Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons. | 2003 Nov 26 |
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11818505 | PI3K is involved in the IGF-I inhibition of TSH-induced sodium/iodide symporter gene expression. | 2002 Feb |
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| 34 |
12021190 | Follicle-stimulating hormone amplifies insulin-like growth factor I-mediated activation of AKT/protein kinase B signaling in immature rat Sertoli cells. | 2002 Jun |
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| 35 |
11208901 | Survival activity of troglitazone in rat motoneurones. | 2001 Jan |
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| 36 |
11228094 | Insulin-like growth factor-1 protects H9c2 cardiac myoblasts from oxidative stress-induced apoptosis via phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways. | 2001 Jan 26 |
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| 37 |
11349832 | Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling. | 2001 Apr |
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| 38 |
11517177 | LY 294002, an inhibitor of phosphatidylinositol 3-kinase, inhibits GH-mediated expression of the IGF-I gene in rat hepatocytes. | 2001 Sep |
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| 39 |
11521195 | The role of the insulin receptor substrate-1 in the differentiation of rat hippocampal neuronal cells. | 2001 Aug 9 |
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| 40 |
10713398 | Insulin-like growth factor-1-mediated protection from neuronal apoptosis is linked to phosphorylation of the pro-apoptotic protein BAD but not to inhibition of cytochrome c translocation in rat cerebellar neurons. | 2000 Mar 17 |
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| 41 |
10788447 | Stimulation of protein kinase C modulates insulin-like growth factor-1-induced akt activation in PC12 cells. | 2000 May 5 |
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| 42 |
10816436 | Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells. | 2000 Jun 1 |
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10868937 | Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: involvement of phosphatidylinositol 3-kinase. | 2000 Feb |
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| 44 |
10579338 | Insulin-like growth factor signaling pathways in rat hepatic stellate cells: importance for deoxyribonucleic acid synthesis and hepatocyte growth factor production. | 1999 Dec |
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10590177 | Insulin-like growth factor-I prevents caspase-mediated apoptosis in Schwann cells. | 1999 Dec |
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| 46 |
9030615 | Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling. | 1997 Mar 1 |
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9139803 | Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes. | 1997 May |
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| 48 |
7852343 | Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin or LY294002 but not by rapamycin or by inhibiting p21ras. | 1995 Feb 10 |
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