Protein Name mitogen activated protein kinase 3
Organism Rattus norvegicus
Gene ID 50689
Gene Symbol

Mapk3

UniProt P21708 (MK03_RAT)
Relationships Total Number of functionally related compound(s) : 1665
Total Number of Articles : 3349
Description

mitogen activated protein kinase 3

Gene Summary

Enables ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including arachidonic acid metabolic process; decidualization; and peptidyl-serine phosphorylation. Located in caveola; cytosol; and nucleoplasm. Part of protein-containing complex. Used to study gastric ulcer; middle cerebral artery infarction; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • mitogen-activated protein kinase 3
  • MAP kinase 1
  • MAP kinase 3
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Properties