Protein Name mitogen activated protein kinase 3
Organism Rattus norvegicus
Gene ID 50689
Gene Symbol

Mapk3

UniProt P21708 (MK03_RAT)
Relationships Total Number of functionally related compound(s) : 1665
Total Number of Articles : 3349
Description

mitogen activated protein kinase 3

Gene Summary

Enables ATP binding activity; MAP kinase activity; and scaffold protein binding activity. Involved in several processes, including arachidonate metabolic process; decidualization; and peptidyl-serine phosphorylation. Located in caveola; cytoplasm; and nucleoplasm. Part of protein-containing complex. Used to study several diseases, including alcohol dependence; cocaine abuse; drug dependence (multiple); gastric ulcer; and middle cerebral artery infarction. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in Parkinson's disease; carcinoma (multiple); and pulmonary hypertension. Orthologous to human MAPK3 (mitogen-activated protein kinase 3). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • mitogen-activated protein kinase 3
  • MAP kinase 1
  • MAP kinase 3
Click to show/hide the synonyms
Properties