| 1 |
34558536 | Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury. | 2022 May |
1 |
| 2 |
33846811 | Synergistic effects of LY294002 and ABT199 on the cell cycle in K562, HL60 and KG1a cells. | 2021 Jun |
1 |
| 3 |
34339756 | DG-8d, a novel diosgenin derivative, decreases the proliferation and induces the apoptosis of A549 cells by inhibiting the PI3k/Akt signaling pathway. | 2021 Oct |
1 |
| 4 |
34697781 | Jolkinolide B attenuates laryngeal cancer cell growth and induces apoptosis via PTEN/PI3K/Akt signaling pathway. | 2021 Sep |
1 |
| 5 |
32463592 | CFTR promotes malignant glioma development via up-regulation of Akt/Bcl2-mediated anti-apoptosis pathway. | 2020 Jul |
1 |
| 6 |
32691555 | [Nano-silicon Dioxide Affects Apoptosis of Alveolar Macrophages via PI3K/AKt Signaling Pathway]. | 2020 Jul |
1 |
| 7 |
32722075 | Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells. | 2020 Jul 24 |
2 |
| 8 |
32922037 | CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling. | 2020 |
1 |
| 9 |
31786865 | Apatinib suppresses the Proliferation and Apoptosis of Gastric Cancer Cells via the PI3K/Akt Signaling Pathway. | 2019 Sep-Oct |
2 |
| 10 |
29263137 | Functional blocking of Ninjurin1 as a strategy for protecting endothelial cells in diabetes mellitus. | 2018 Jan 31 |
1 |
| 11 |
29545835 | Expression and phosphorylation of FOXO1 influences cell proliferation and apoptosis in the gastrointestinal stromal tumor cell line GIST-T1. | 2018 Apr |
3 |
| 12 |
30061946 | CCL2 influences the sensitivity of lung cancer A549 cells to docetaxel. | 2018 Jul |
1 |
| 13 |
28775672 | Regulatory effects of COL1A1 on apoptosis induced by radiation in cervical cancer cells. | 2017 |
1 |
| 14 |
28789432 | Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer. | 2017 Aug |
1 |
| 15 |
29071206 | Estrogen receptor β exhibited anti-tumor effects on osteosarcoma cells by regulating integrin, IAP, NF-kB/BCL-2 and PI3K/Akt signal pathway. | 2017 Nov |
1 |
| 16 |
26796279 | The inhibition of PI3K and NFκB promoted curcumin-induced cell cycle arrest at G2/M via altering polyamine metabolism in Bcl-2 overexpressing MCF-7 breast cancer cells. | 2016 Feb |
2 |
| 17 |
25510413 | Survival-apoptosis associated signaling in GNE myopathy-cultured myoblasts. | 2015 |
2 |
| 18 |
25960232 | Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells. | 2015 Apr |
1 |
| 19 |
26256949 | Hypoxia-mediated cancer stem cells in pseudopalisades with activation of hypoxia-inducible factor-1α/Akt axis in glioblastoma. | 2015 Oct |
1 |
| 20 |
23910058 | In vitro regulation of hepatocellular carcinoma cell viability, apoptosis, invasion, and AEG-1 expression by LY294002. | 2014 Feb |
1 |
| 21 |
24476894 | ARHI overexpression induces epithelial ovarian cancer cell apoptosis and excessive autophagy. | 2014 Mar |
1 |
| 22 |
24757411 | Fragile histidine triad (FHIT) suppresses proliferation and promotes apoptosis in cholangiocarcinoma cells by blocking PI3K-Akt pathway. | 2014 |
1 |
| 23 |
24941119 | AEG-1 promotes anoikis resistance and orientation chemotaxis in hepatocellular carcinoma cells. | 2014 |
1 |
| 24 |
23420486 | Synergistic lethality of mifepristone and LY294002 in ovarian cancer cells. | 2013 |
1 |
| 25 |
23743572 | Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine. | 2013 Aug |
1 |
| 26 |
21749866 | Chlorogenic acid protects MSCs against oxidative stress by altering FOXO family genes and activating intrinsic pathway. | 2012 Jan 15 |
2 |
| 27 |
22086271 | LY294002 enhances cytotoxicity of temozolomide in glioma by down-regulation of the PI3K/Akt pathway. | 2012 Feb |
1 |
| 28 |
21130731 | Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2. | 2011 Feb 18 |
2 |
| 29 |
21320517 | The neuroprotective action of pyrroloquinoline quinone against glutamate-induced apoptosis in hippocampal neurons is mediated through the activation of PI3K/Akt pathway. | 2011 Apr 1 |
1 |
| 30 |
21468550 | microRNA-21 modulates cell proliferation and sensitivity to doxorubicin in bladder cancer cells. | 2011 Jun |
1 |
| 31 |
21765100 | Different effects of corticotropin-releasing factor and urocortin 2 on apoptosis of prostate cancer cells in vitro. | 2011 Oct |
1 |
| 32 |
19709444 | Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis. | 2009 |
1 |
| 33 |
18356276 | Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors. | 2008 Jul |
1 |
| 34 |
19051078 | Phosphoinositide 3-kinase/Akt signalling is responsible for the differential susceptibility of myoblasts and myotubes to menadione-induced oxidative stress. | 2008 Sep |
1 |
| 35 |
17234779 | Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells. | 2007 Jan 15 |
1 |
| 36 |
16546963 | Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis. | 2006 Mar |
2 |
| 37 |
16162974 | Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria. | 2005 Oct |
1 |
| 38 |
14605879 | Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45. | 2004 Jan |
1 |
| 39 |
15292252 | p38 MAPK mediates gamma-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway. | 2004 Oct 8 |
1 |
| 40 |
12663669 | Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis. | 2003 Jun 6 |
1 |
| 41 |
12731064 | TGF-beta1 modulates Fas (APO-1/CD95)-mediated apoptosis of human pre-B cell lines. | 2003 May |
1 |
| 42 |
12879014 | Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3'-kinase (PI3K) pathway is inhibited. | 2003 Jul 24 |
1 |
| 43 |
12056831 | Activation of Erk1/2 and Akt in astrocytes under ischemia. | 2002 Jun 14 |
1 |
| 44 |
11767000 | Cytotoxicity induced by manipulation of signal transduction pathways is associated with down-regulation of Bcl-2 but not Mcl-1 in MCF-7 human breast cancer. | 2001 Nov |
2 |