2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

nuclear factor kappa B subunit 1 ; Homo sapiens







85 Article(s)
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1 35500642 Astaxanthin ameliorates hyperglycemia induced inflammation via PI3K/Akt-NF-κB signaling in ARPE-19 cells and diabetic rat retina. 2022 Jul 5 1
2 34419144 AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway. 2021 Aug 21 1
3 31756335 Triptolide inhibits PDGF-induced proliferation of ASMCs through G0/G1 cell cycle arrest and suppression of the AKT/NF-κB/cyclinD1 signaling pathway. 2020 Jan 15 1
4 32174780 Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma. 2020 1
5 32318240 Kaji-Ichigoside F1 and Rosamultin Protect Vascular Endothelial Cells against Hypoxia-Induced Apoptosis via the PI3K/AKT or ERK1/2 Signaling Pathway. 2020 1
6 32552933 [Effect of Bmi-1 on Multidrug Resistance in K562/ADR Cells and Its Mechanisms]. 2020 Jun 2
7 32602017 Protective effects of acetylcholine on hypoxia-induced endothelial-to-mesenchymal transition in human cardiac microvascular endothelial cells. 2020 Oct 1
8 30260006 Pingchuanning decoction attenuates airway inflammation by suppressing autophagy via phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway in rat models of asthma. 2019 Mar 1
9 31026389 Praeruptorin-B Inhibits 12-O-Tetradecanoylphorbol-13-Acetate-Induced Cell Invasion by Targeting AKT/NF-κB via Matrix Metalloproteinase-2/-9 Expression in Human Cervical Cancer Cells. 2019 1
10 31068539 Titanium dioxide nanoparticles induce COX-2 expression through ROS generation in human periodontal ligament cells. 2019 1
11 29330470 β-Ecdysterone protects SH-SY5Y cells against β-amyloid-induced apoptosis via c-Jun N-terminal kinase- and Akt-associated complementary pathways. 2018 Apr 1
12 29427163 Anti-Inflammatory Effects of Hypophyllanthin and Niranthin Through Downregulation of NF-κB/MAPKs/PI3K-Akt Signaling Pathways. 2018 Jun 1
13 29512729 Curcumin inhibits superoxide dismutase-induced epithelial-to-mesenchymal transition via the PI3K/Akt/NF-κB pathway in pancreatic cancer cells. 2018 May 1
14 29577981 Perfluorooctane sulfonate mediates secretion of IL-1β through PI3K/AKT NF-кB pathway in astrocytes. 2018 May - Jun 1
15 28057758 Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. 2017 Feb 10 2
16 28288190 Tetrandrine inhibits migration and invasion of human renal cell carcinoma by regulating Akt/NF-κB/MMP-9 signaling. 2017 1
17 28385482 Nicotine promotes cervical carcinoma cell line HeLa migration and invasion by activating PI3k/Akt/NF-κB pathway in vitro. 2017 Jul 5 1
18 27125675 Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-κB Signaling Pathways. 2016 Jun 1
19 26453509 Cucurbitacin E inhibits TNF-α-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-κB pathways. 2015 Dec 1
20 26522351 [BAY11-7082 inhibits proliferation and promotes apoptosis in breast carcinoma MCF-7 cells by inhibiting phosphorylation of ATP citrate lyase]. 2015 Nov 1
21 24206109 Stimulating ERK/PI3K/NFκB signaling pathways upon activation of mGluR2/3 restores OGD-induced impairment in glutamate clearance in astrocytes. 2014 Jan 1
22 24506791 Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/Akt-dependent NF-κB/p300 activation. 2014 Aug 2
23 24760275 Prostaglandin E2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells. 2014 Jul 1
24 24939823 Jaceosidin, a natural flavone, promotes angiogenesis via activation of VEGFR2/FAK/PI3K/AKT/NF-κB signaling pathways in endothelial cells. 2014 Oct 1
25 25085593 Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway. 2014 Aug 1 2
26 23229346 Lapatinib inhibits the activation of NF-κB through reducing phosphorylation of IκB-α in breast cancer cells. 2013 Feb 1
27 23255946 Piceatannol inhibits MMP-9-dependent invasion of tumor necrosis factor-α-stimulated DU145 cells by suppressing the Akt-mediated nuclear factor-κB pathway. 2013 Jan 1
28 23383347 Epidermal growth factor protects squamous cell carcinoma against cisplatin-induced cytotoxicity through increased interleukin-1β expression. 2013 2
29 23449446 Nuclear factor-κB modulates osteogenesis of periodontal ligament stem cells through competition with β-catenin signaling in inflammatory microenvironments. 2013 Feb 28 1
30 23564227 House dust mite allergen Der f 2 induces interleukin-13 expression by activating the PI3K/Akt pathway. 2013 May 1
31 23603894 Inhibition of the PI3K/AKT-NF-κB pathway with curcumin enhanced radiation-induced apoptosis in human Burkitt's lymphoma. 2013 1
32 23791833 Interleukin-6 upregulates paraoxonase 1 gene expression via an AKT/NF-κB-dependent pathway. 2013 Jul 19 1
33 23992306 Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-κB pathway. 2013 1
34 24244375 HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-κB, AP-1, C/EBPα and C/EBPγ transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways. 2013 1
35 22005520 The phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 modulates cytokine expression in macrophages via p50 nuclear factor κB inhibition, in a PI3K-independent mechanism. 2012 Jan 1 9
36 22193240 Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways. 2012 Jan 1
37 22419429 Ethanol extract of Graptopetalum paraguayense upregulates paraoxonase 1 gene expression via an AKT/NF-κB-dependent pathway. 2012 1
38 22455747 [Effects of PI3K/Akt/NF-κB signal pathway on FSH facilitation on cell proliferation and invasion by human epithelial ovarian cancer]. 2012 Feb 1
39 22459175 PI3-K/Akt/JNK/NF-κB is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane. 2012 Jul 1
40 22975513 Interferon gamma induces steroid sulfatase expression in human keratinocytes. 2012 1
41 21245990 LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway. 2011 Jan 14 3
42 21276823 Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression. 2011 May 1
43 21422731 Hyaluronan inhibits Akt, leading to nuclear factor-κB down-regulation in lipopolysaccharide-stimulated U937 macrophages. 2011 1
44 20649564 IL-1beta induces expression of matrix metalloproteinase-9 and cell migration via a c-Src-dependent, growth factor receptor transactivation in A549 cells. 2010 Aug 2
45 20947290 Blocking of PI3K/AKT induces apoptosis by its effect on NF-κB activity in gastric carcinoma cell line SGC7901. 2010 Nov 1
46 19301309 Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells. 2009 Jul 1 1
47 19428548 NF-kappaB inhibition leads to increased synthesis and secretion of MIF in human CD4+ T cells. 2009 Mar 24 1
48 19717552 Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells. 2009 Nov 1
49 20120770 Phosphoinositide 3-kinase/Akt and nuclear factor-kappaB are involved in Staphylococcus aureus-induced apoptosis in U937 cells. 2009 Dec 1
50 17849421 Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas. 2008 Feb 1