Protein Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Organism Homo sapiens
Gene ID 5293
Gene Symbol

PIK3CD

UniProt O00329 (PK3CD_HUMAN), A0A2K8FKV1 (A0A2K8FKV1_HUMAN)
Relationships Total Number of functionally related compound(s) : 775
Total Number of Articles : 1517
Description

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

Gene Summary

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]

synonyms
  • phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • PI3-kinase p110 subunit delta
  • PI3Kdelta
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Properties