Protein Name mitogen-activated protein kinase 3
Organism Homo sapiens
Gene ID 5595
Gene Symbol


UniProt P27361 (MK03_HUMAN), L7RXH5 (L7RXH5_HUMAN), Q9BWJ1 (Q9BWJ1_HUMAN)
Relationships Total Number of functionally related compound(s) : 3238
Total Number of Articles : 8273

mitogen-activated protein kinase 3

Gene Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]

  • mitogen-activated protein kinase 3
  • MAPK 1
  • extracellular signal-regulated kinase 1
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