| Protein Name | mitogen-activated protein kinase 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5595 |
| Gene Symbol | MAPK3 |
| UniProt | P27361 (MK03_HUMAN), L7RXH5 (L7RXH5_HUMAN), Q9BWJ1 (Q9BWJ1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
3238
Total Number of Articles : 8273 |
Description |
mitogen-activated protein kinase 3 |
| Gene Summary |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008] |
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