Protein Name heme oxygenase 1
Organism Homo sapiens
Gene ID 3162
Gene Symbol

HMOX1

UniProt P09601 (HMOX1_HUMAN), Q6FH11 (Q6FH11_HUMAN)
Relationships Total Number of functionally related compound(s) : 1764
Total Number of Articles : 3556
Description

heme oxygenase 1

Gene Summary

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]

synonyms
  • heme oxygenase 1
  • heat shock protein, 32-kD
  • heme oxygenase (decycling) 1
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Properties