| Protein Name | BCL2, apoptosis regulator |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24224 |
| Gene Symbol | Bcl2 |
| UniProt | P49950 (BCL2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
1676
Total Number of Articles : 3685 |
Description |
BCL2, apoptosis regulator |
| Gene Summary |
Enables BH domain binding activity. Involved in several processes, including response to peptide; response to purine-containing compound; and response to vitamin. Located in cytosol; mitochondrial crista; and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple); end stage renal disease; gastric ulcer; intestinal disease (multiple); and status epilepticus. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1; brain disease (multiple); hypertension (multiple); intrinsic cardiomyopathy (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator). [provided by Alliance of Genome Resources, Apr 2022] |
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