2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ; Rattus norvegicus







87 Article(s)
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1 34874518 Xuebijing Injection Ameliorates H2S-Induced Acute Respiratory Distress Syndrome by Promoting Claudin-5 Expression. 2022 Feb 1
2 35309056 Inhibition of PI3K/AKT/mTOR Signalling Pathway Activates Autophagy and Suppresses Peritoneal Fibrosis in the Process of Peritoneal Dialysis. 2022 1
3 33188898 Protection by rhynchophylline against MPTP/MPP+-induced neurotoxicity via regulating PI3K/Akt pathway. 2021 Mar 25 1
4 33481205 S-oxiracetam Facilitates Cognitive Restoration after Ischemic Stroke by Activating α7nAChR and the PI3K-Mediated Pathway. 2021 Apr 1
5 34506777 Dexmedetomidine protects the heart against ischemia reperfusion injury via regulation of the bradykinin receptors. 2021 Nov 15 1
6 32507927 Effect of Methylene Blue and PI3K-Akt Pathway Inhibitors on the Neurovascular System after Chronic Cerebral Hypoperfusion in Rats. 2020 Nov 1
7 31001561 A New Way for Beta Cell Neogenesis: Transdifferentiation from Alpha Cells Induced by Glucagon-Like Peptide 1. 2019 1
8 31570094 The role of PI3K-mediated AMPA receptor changes in post-conditioning of propofol in brain protection. 2019 Oct 1 1
9 31920923 A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse. 2019 1
10 30075219 DHA attenuates hepatic ischemia reperfusion injury by inhibiting pyroptosis and activating PI3K/Akt pathway. 2018 Sep 15 1
11 25136768 Insulin-like growth factor-1 attenuates apoptosis and protects neurochemical phenotypes of dorsal root ganglion neurons with paclitaxel-induced neurotoxicity in vitro. 2017 Feb 1
12 28129651 Activation of PI3K in response to high glucose leads to regulation of SOCS-3 and STAT1/3 signals and induction of glomerular mesangial extracellular matrix formation. 2017 Mar 7 1
13 28210955 The Effects of IGF-1 on TNF-α-Treated DRG Neurons by Modulating ATF3 and GAP-43 Expression via PI3K/Akt/S6K Signaling Pathway. 2017 May 1
14 28536643 Icariin Prevents H2O2-Induced Apoptosis via the PI3K/Akt Pathway in Rat Nucleus Pulposus Intervertebral Disc Cells. 2017 1
15 28614771 Mantidis ootheca induces vascular relaxation through PI3K/AKT-mediated nitric oxide-cyclic GMP-protein kinase G signaling in endothelial cells. 2017 Apr 1
16 28785775 T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway. 2017 Nov 1
17 28993734 Osmotin Protects H9c2 Cells from Simulated Ischemia-Reperfusion Injury through AdipoR1/PI3K/AKT Signaling Pathway. 2017 1
18 29037812 Apolipoprotein A-IV exerts its anorectic action through a PI3K/Akt signaling pathway in the hypothalamus. 2017 Dec 9 1
19 26414235 Protection afforded by quercetin against H2O2-induced apoptosis on PC12 cells via activating PI3K/Akt signal pathway. 2016 1
20 26647727 PI3K/Akt signaling pathway is involved in the neurotrophic effect of senegenin. 2016 Feb 1
21 26717963 Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. 2016 Feb 1
22 27372651 Geniposide Prevents Hypoxia/Reoxygenation-Induced Apoptosis in H9c2 Cells: Improvement of Mitochondrial Dysfunction and Activation of GLP-1R and the PI3K/AKT Signaling Pathway. 2016 1
23 25201632 Acetylcholine inhibits tumor necrosis factor α activated endoplasmic reticulum apoptotic pathway via EGFR-PI3K signaling in cardiomyocytes. 2015 Apr 1
24 25806690 Resolvin D1 Reduces Infarct Size Through a Phosphoinositide 3-Kinase/Protein Kinase B Mechanism. 2015 Jul 1
25 26211446 17β-Estradiol up-regulates Nrf2 via PI3K/AKT and estrogen receptor signaling pathways to suppress light-induced degeneration in rat retina. 2015 Sep 24 1
26 26492644 Cardioprotective effect of breviscapine: inhibition of apoptosis in H9c2 cardiomyocytes via the PI3K/Akt/eNOS pathway following simulated ischemia/reperfusion injury. 2015 Sep 1
27 24212403 C1q tumor necrosis factor-related protein-3 protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis through the phosphoinositide 3-kinase/Akt pathway. 2014 Jan 1
28 24296153 Effects of antidepressant drugs on synaptic protein levels and dendritic outgrowth in hippocampal neuronal cultures. 2014 Apr 1
29 24446161 Insulin stimulates the expression of the SHARP-1 gene via multiple signaling pathways. 2014 Jun 1
30 24939171 Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia. 2014 Nov 1
31 23069760 PI3K/Akt and NF-κB activation following intravitreal administration of 17β-estradiol: neuroprotection of the rat retina from light-induced apoptosis. 2013 Jan 3 1
32 23124851 Chronic treatment with LY294002, an inhibitor of phosphatidylinositol 3-kinase, attenuates ischemia/reperfusion-induced cardiac dysfunction in normotensive and hypertensive diabetic animals. 2013 Jan 1
33 24351811 Neuritogenic monoglyceride derived from the constituent of a marine fish for activating the PI3K/ERK/CREB signalling pathways in PC12 cells. 2013 Dec 12 1
34 21964769 The Akt/FoxO1/p27 pathway mediates the proliferative action of liraglutide in β cells. 2012 Jan 1
35 22222440 Neuroprotective effect of fucoidan on H2O2-induced apoptosis in PC12 cells via activation of PI3K/Akt pathway. 2012 May 1
36 22402346 The protective effect of sonic hedgehog is mediated by the phosphoinositide [corrected] 3-kinase/AKT/Bcl-2 pathway in cultured rat astrocytes under oxidative stress. 2012 May 3 1
37 22490886 Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells. 2012 May 10 1
38 22828749 PI3K/Akt signaling pathway in the basolateral amygdala mediates the rapid antidepressant-like effects of trefoil factor 3. 2012 Nov 1
39 23000625 Exendin-4 improved rat cortical neuron survival under oxygen/glucose deprivation through PKA pathway. 2012 Dec 13 1
40 23271286 Involvement of PI3K/Akt pathway in the neuroprotective effect of Sonic hedgehog on cortical neurons under oxidative stress. 2012 Dec 1
41 21347252 Neurotrophic effects of a cyanine dye via the PI3K-Akt pathway: attenuation of motor discoordination and neurodegeneration in an ataxic animal model. 2011 Feb 11 1
42 22025881 Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3. 2011 Sep 14 1
43 19766678 Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78. 2010 Jan 1
44 20188023 Aromatase gene expression in immature rat Sertoli cells: age-related changes in the FSH signalling pathway. 2010 1
45 18799305 A novel biomimetic olfactory-based biosensor for single olfactory sensory neuron monitoring. 2009 Jan 1 1
46 19277909 Serum albumin protects from cytokine-induced pancreatic beta cell death by a phosphoinositide 3-kinase-dependent mechanism. 2009 Jun 1
47 19353747 Response enhancement of olfactory sensory neurons-based biosensors for odorant detection. 2009 Apr 1
48 19381068 Angiotensin II-induced aortic ring constriction is mediated by phosphatidylinositol 3-kinase/L-type calcium channel signaling pathway. 2009 Aug 31 1
49 18303854 Insulinomimetic effect of kaempferol 3-neohesperidoside on the rat soleus muscle. 2008 Apr 1
50 18367589 IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells. 2008 May 1