| 1 |
34349085 | Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway. | 2022 Feb 9 |
1 |
| 2 |
34522005 | mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1-GluA2 interaction in the nucleus accumbens. | 2022 Feb |
1 |
| 3 |
34553399 | Fraxetin suppresses reactive oxygen species-dependent autophagy by the PI3K/Akt pathway to inhibit isoflurane-induced neurotoxicity in hippocampal neuronal cells. | 2022 Apr |
1 |
| 4 |
34597809 | Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models. | 2022 Mar |
1 |
| 5 |
34865170 | Allosteric Modulation of the Sigma-1 Receptor Elicits Antipsychotic-like Effects. | 2022 Mar 1 |
1 |
| 6 |
34874107 | Alpinae Oxyphyllae Fructus alleviated LPS-induced cognitive impairments via PI3K/AKT/NF-κB signaling pathway. | 2022 Mar |
1 |
| 7 |
35053144 | A TRICk to Improve the Effectiveness of RIC: Role of Limb Temperature in Enhancing the Effectiveness of Remote Ischemic Conditioning. | 2022 Jan 17 |
1 |
| 8 |
35066448 | Exogenous pancreatic kininogenase protects against tacrolimus-induced renal injury by inhibiting PI3K/AKT signaling: The role of bradykinin receptors. | 2022 Apr |
1 |
| 9 |
35130910 | Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway. | 2022 Feb 7 |
1 |
| 10 |
35132190 | CB2 receptor activation inhibits the phagocytic function of microglia through activating ERK/AKT-Nurr1 signal pathways. | 2022 Feb 7 |
2 |
| 11 |
35165685 | Eucalyptol targets PI3K/Akt/mTOR Pathway to inhibit Skin Cancer Metastasis. | 2022 Feb 15 |
1 |
| 12 |
35201262 | The Therapeutic Roles of Recombinant Hsp90α on Cornea Epithelial Injury. | 2022 Feb 1 |
1 |
| 13 |
35261236 | Targeting MicroRNA-144/451-AKT-GSK3β Axis Affects the Proliferation and Differentiation of Radial Glial Cells in the Mouse Hippocampal Dentate Gyrus. | 2022 Apr 6 |
1 |
| 14 |
35282120 | Asiaticoside alleviates cardiomyocyte apoptosis and oxidative stress in myocardial ischemia/reperfusion injury via activating the PI3K-AKT-GSK3β pathway in vivo and in vitro. | 2022 Jan |
1 |
| 15 |
35354939 | Gene knockdown of CCR3 reduces eosinophilic inflammation and the Th2 immune response by inhibiting the PI3K/AKT pathway in allergic rhinitis mice. | 2022 Mar 30 |
1 |
| 16 |
35355710 | Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway. | 2022 |
1 |
| 17 |
35359221 | Integrinβ3 mediates the protective effects of soluble receptor for advanced glycation end-products during myocardial ischemia/reperfusion through AKT/STAT3 signaling pathway. | 2022 Jun |
2 |
| 18 |
35378205 | Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway. | 2022 May |
1 |
| 19 |
35394554 | Fractalkine deficiency attenuates LPS-induced acute kidney injury and podocyte apoptosis by targeting the PI3K/Akt signal pathway. | 2022 Apr 8 |
2 |
| 20 |
35484750 | Bioactive Small Molecule Enhances Skin Burn Wound Healing and Hair Follicle Regeneration by Activating PI3K/AKT Signaling Pathway: A Preclinical Evaluation in Animal Model. | 2022 Feb 1 |
2 |
| 21 |
35487953 | sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K-AKT signaling pathway. | 2022 Apr 29 |
1 |
| 22 |
35503228 | The Protective Effects of KAT5 Inhibition on Ocular Inflammation by Mediating the PI3K/AKT Pathway in a Murine Model of Allergic Conjunctivitis. | 2022 May 2 |
1 |
| 23 |
35533447 | Asthma susceptibility in prenatal nicotine-exposed mice attributed to β-catenin increase during CD4+ T cell development. | 2022 Jun 15 |
1 |
| 24 |
35550264 | Sevoflurane suppresses NLRP3 inflammasome-mediated pyroptotic cell death to attenuate lipopolysaccharide-induced acute lung injury through inducing GSK-3β phosphorylation and activation. | 2022 Aug |
1 |
| 25 |
35575872 | Cryptotanshinone Attenuates Amyloid-β42-induced Tau Phosphorylation by Regulating PI3K/Akt/GSK3β Pathway in HT22 Cells. | 2022 Jul |
1 |
| 26 |
35582997 | Notch1/Hes1‑PTEN/AKT/IL‑17A feedback loop regulates Th17 cell differentiation in mouse psoriasis‑like skin inflammation. | 2022 Jul |
6 |
| 27 |
32668051 | Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis. | 2021 Jan |
2 |
| 28 |
32811251 | Protease-activated receptor 4 causes Akt phosphorylation independently of PI3 kinase pathways. | 2021 Aug 18 |
3 |
| 29 |
32942336 | Clusterin suppresses spermatogenic cell apoptosis to alleviate diabetes-induced testicular damage by inhibiting autophagy via the PI3K/AKT/mTOR axis. | 2021 Jan |
1 |
| 30 |
33414476 | METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial-mesenchymal transition of renal tubular cells in diabetic kidney disease. | 2021 Jan 4 |
2 |
| 31 |
33432947 | Resveratrol attenuates dapagliflozin-induced renal gluconeogenesis via activating the PI3K/Akt pathway and suppressing the FoxO1 pathway in type 2 diabetes. | 2021 Feb 15 |
1 |
| 32 |
33456508 | 4-Octyl itaconate (4-OI) attenuates lipopolysaccharide-induced acute lung injury by suppressing PI3K/Akt/NF-κB signaling pathways in mice. | 2021 Feb |
1 |
| 33 |
33537812 | FBXW7 mediates high glucose‑induced SREBP‑1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation. | 2021 Apr |
1 |
| 34 |
33537834 | Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification. | 2021 Apr |
1 |
| 35 |
33603340 | Loganin Attenuates Septic Acute Renal Injury with the Participation of AKT and Nrf2/HO-1 Signaling Pathways. | 2021 |
1 |
| 36 |
33607158 | XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury. | 2021 May 1 |
2 |
| 37 |
33632134 | Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway. | 2021 Feb 25 |
1 |
| 38 |
33645479 | Connectivity Map Analysis Identifies Fisetin as a Treatment Compound for Osteoporosis Through Activating the PI3K-AKT Signaling Pathway in Mouse Pre-osteoblastic MC3T3-E1 Cells. | 2021 |
1 |
| 39 |
33710186 | Bioactive compound from the Tibetan turnip (Brassica rapa L.) elicited anti-hypoxia effects in OGD/R-injured HT22 cells by activating the PI3K/AKT pathway. | 2021 Apr 7 |
1 |
| 40 |
33804171 | Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell. | 2021 Mar 15 |
1 |
| 41 |
33860870 | PI3K/AKT/mTOR and TLR4/MyD88/NF-κB Signaling Inhibitors Attenuate Pathological Mechanisms of Allergic Asthma. | 2021 Oct |
1 |
| 42 |
33986917 | Inactivation of TOPK Caused by Hyperglycemia Blocks Diabetic Heart Sensitivity to Sevoflurane Postconditioning by Impairing the PTEN/PI3K/Akt Signaling. | 2021 |
1 |
| 43 |
33999329 | Isorhamnetin Alleviates High Glucose-Aggravated Inflammatory Response and Apoptosis in Oxygen-Glucose Deprivation and Reoxygenation-Induced HT22 Hippocampal Neurons Through Akt/SIRT1/Nrf2/HO-1 Signaling Pathway. | 2021 Oct |
1 |
| 44 |
34038756 | Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death. | 2021 Jul |
1 |
| 45 |
34118791 | Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway. | 2021 Jun 11 |
1 |
| 46 |
34275490 | Pharmacological inhibition of the PI3K/PTEN/Akt and mTOR signalling pathways limits follicle activation induced by ovarian cryopreservation and in vitro culture. | 2021 Jul 19 |
1 |
| 47 |
34332284 | 2,6-Dimethoxy-1,4-benzoquinone increases skeletal muscle mass and performance by regulating AKT/mTOR signaling and mitochondrial function. | 2021 Oct |
1 |
| 48 |
34358859 | Methyl eugenol attenuates liver ischemia reperfusion injury via activating PI3K/Akt signaling. | 2021 Oct |
2 |
| 49 |
34416638 | Triclosan-induced glycolysis drives inflammatory activation in microglia via the Akt/mTOR/HIF 1α signaling pathway. | 2021 Aug 17 |
1 |
| 50 |
34425525 | LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice. | 2021 Dec |
1 |