CPRiL

Protein Name	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Organism	Homo sapiens
Gene ID	5290
Gene Symbol	PIK3CA
UniProt	P42336 (PK3CA_HUMAN), Q4LE51 (Q4LE51_HUMAN)
Relationships	Total Number of functionally related compound(s) : 683 Total Number of Articles : 1080
Description	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Gene Summary	Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]
synonyms	phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PI3-kinase p110 subunit alpha mutant phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha phosphatidylinositol 3-kinase, catalytic, alpha polypeptide phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha phosphoinositide 3-kinase alpha phosphoinositide-3-kinase, catalytic, alpha polypeptide ptdIns-3-kinase subunit p110-alpha serine/threonine protein kinase PIK3CA CCM4 CLAPO CLOVE CWS5 HMH MCAP MCM MCMTC PI3K PI3K-alpha p110-alpha Click to show/hide the synonyms
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