| Protein Name | BCL2 apoptosis regulator |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 596 |
| Gene Symbol | BCL2 |
| UniProt | P10415 (BCL2_HUMAN), A0A024R2B3 (A0A024R2B3_HUMAN), A0A024R2C4 (A0A024R2C4_HUMAN), A0A7I2V3S7 (A0A7I2V3S7_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
4403
Total Number of Articles : 12492 |
Description |
BCL2 apoptosis regulator |
| Gene Summary |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
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