Protein Name glycogen synthase kinase 3 beta
Organism Homo sapiens
Gene ID 2932
Gene Symbol


UniProt P49841 (GSK3B_HUMAN), Q6FI27 (Q6FI27_HUMAN)
Relationships Total Number of functionally related compound(s) : 1189
Total Number of Articles : 2271

glycogen synthase kinase 3 beta

Gene Summary

The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]

  • glycogen synthase kinase-3 beta
  • GSK-3 beta
  • serine/threonine-protein kinase GSK3B
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