Protein Name | glycogen synthase kinase 3 beta |
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Organism | Homo sapiens |
Gene ID | 2932 |
Gene Symbol | GSK3B |
UniProt | P49841 (GSK3B_HUMAN), Q6FI27 (Q6FI27_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
1189
Total Number of Articles : 2271 |
Description |
glycogen synthase kinase 3 beta |
Gene Summary |
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017] |
synonyms |
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Properties | |