Protein Name NFE2 like bZIP transcription factor 2
Organism Homo sapiens
Gene ID 4780
Gene Symbol

NFE2L2

UniProt Q16236 (NF2L2_HUMAN)
Relationships Total Number of functionally related compound(s) : 2545
Total Number of Articles : 5461
Description

NFE2 like bZIP transcription factor 2

Gene Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]

synonyms
  • nuclear factor erythroid 2-related factor 2
  • nuclear factor erythroid-derived 2-like 2
  • nuclear factor, erythroid 2 like 2
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Properties