2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

insulin-like growth factor 1 ; Mus musculus







30 Article(s)
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1 33724692 Cardiomyocyte protective effects of thyroid hormone during hypoxia/reoxygenation injury through activating of IGF-1-mediated PI3K/Akt signalling. 2021 Apr 1
2 34031457 Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium extract (icariin) promoted C2C12 myotube hypertrophy. 2021 May 24 1
3 31018166 IGF-1 reverses the osteogenic inhibitory effect of dexamethasone on BMP9-induced osteogenic differentiation in mouse embryonic fibroblasts via PI3K/AKT/COX-2 pathway. 2019 Jul 1
4 30130150 IGF1 suppresses cholesterol accumulation in the liver of growth hormone-deficient mice via the activation of ABCA1. 2018 Dec 1 1
5 27774572 Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway. 2017 Nov 1
6 25339702 IGF-1 and insulin exert opposite actions on ClC-K2 activity in the cortical collecting ducts. 2015 Jan 1 1
7 26146542 Akt-mediated phosphorylation controls the activity of the Y-box protein MSY3 in skeletal muscle. 2015 1
8 24580070 Proliferation of murine c-kit(pos) cardiac stem cells stimulated with IGF-1 is associated with Akt-1 mediated phosphorylation and nuclear export of FoxO3a and its effect on downstream cell cycle regulators. 2014 Apr 1
9 24582811 Upstream and downstream mechanisms for the promoting effects of IGF-1 on differentiation of spermatogonia to primary spermatocytes. 2014 Apr 17 1
10 24598112 Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells. 2014 Jun 1
11 23472139 Activation of Akt by advanced glycation end products (AGEs): involvement of IGF-1 receptor and caveolin-1. 2013 1
12 22249904 Effects of insulin and insulin-like growth factor 1 on osteoblast proliferation and differentiation: differential signalling via Akt and ERK. 2012 Jun 2
13 22956516 cAMP-dependent regulation of ovulatory response genes is amplified by IGF1 due to synergistic effects on Akt phosphorylation and NF-κB transcription factors. 2012 Nov 1
14 21159855 Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts. 2011 Feb 1
15 19246485 Pluripotency of mouse spermatogonial stem cells maintained by IGF-1- dependent pathway. 2009 Jul 1
16 19657059 IGF-I activates the mouse type IIb myosin heavy chain gene. 2009 Oct 2
17 19855934 Insulin-like growth factor-I-induced androgen receptor activation is mediated by the PI3K/Akt pathway in C2C12 skeletal muscle cells. 2009 Nov 30 3
18 18206295 The involvement of phosphatidylinositol 3-kinase in gonadotropin-releasing hormone-induced gonadotropin alpha- and FSHbeta-subunit genes expression in clonal gonadotroph LbetaT2 cells. 2008 Feb 13 1
19 18718566 IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts. 2008 Nov 1
20 18797142 Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells. 2008 Aug 1
21 16787946 Modulation of the PI 3-kinase-Akt signalling pathway by IGF-I and PTEN regulates the differentiation of neural stem/precursor cells. 2006 Jul 1 1
22 15724079 Insulin-like growth factor-I stimulated DNA replication in mouse endometrial stromal cells. 2005 Jun 1
23 15971148 Possible involvement of phosphatidylinositol 3-kinase/Akt pathway in insulin-like growth factor-I-induced alkaline phosphatase activity in osteoblasts. 2005 May 2
24 16086373 Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion. 2005 Oct 2
25 11500504 Insulin-like growth factor-mediated muscle differentiation: collaboration between phosphatidylinositol 3-kinase-Akt-signaling pathways and myogenin. 2001 Oct 19 3
26 11546773 Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2. 2001 Oct 26 1
27 10976992 Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha. 2000 Sep 2
28 9927327 Requirement for phosphatidylinositol-3'-kinase in cytokine-mediated germ cell survival during fetal oogenesis in the mouse. 1999 Feb 1
29 10092673 Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor kappaB. 1999 Apr 2 2
30 10342860 Segregation of retinoic acid effects on fetal ovarian germ cell mitosis versus apoptosis by requirement for new macromolecular synthesis. 1999 Jun 1