Protein Name ribosomal protein S6 kinase B1
Organism Homo sapiens
Gene ID 6198
Gene Symbol

RPS6KB1

UniProt P23443 (KS6B1_HUMAN)
Relationships Total Number of functionally related compound(s) : 764
Total Number of Articles : 1427
Description

ribosomal protein S6 kinase B1

Gene Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

synonyms
  • ribosomal protein S6 kinase beta-1
  • ribosomal protein S6 kinase I
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
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Properties