| 1 |
34558536 | Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury. | 2022 May |
1 |
| 2 |
33486250 | Curcumin suppresses cell growth and attenuates fluoride-mediated Caspase-3 activation in ameloblast-like LS8 cells. | 2021 Jan 11 |
2 |
| 3 |
33846811 | Synergistic effects of LY294002 and ABT199 on the cell cycle in K562, HL60 and KG1a cells. | 2021 Jun |
2 |
| 4 |
34132431 | Suppression of phosphoinositide 3-kinase/phosphoinositide-dependent kinase-1/serum and glucocorticoid-induced protein kinase pathway. | 2021 Aug |
1 |
| 5 |
34697781 | Jolkinolide B attenuates laryngeal cancer cell growth and induces apoptosis via PTEN/PI3K/Akt signaling pathway. | 2021 Sep |
1 |
| 6 |
31992313 | The protective effects of PI3K/Akt pathway on human nucleus pulposus mesenchymal stem cells against hypoxia and nutrition deficiency. | 2020 Jan 28 |
1 |
| 7 |
32173422 | Akt/survivin pathway inhibition enhances the apoptotic cell death-induced by alpha-santalol in human prostate cancer cells. | 2020 Jun |
2 |
| 8 |
32495214 | The role of autophagy in the cytotoxicity induced by trastuzumab emtansine (T-DM1) in HER2-positive breast cancer cells. | 2020 Jun 3 |
1 |
| 9 |
32722075 | Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells. | 2020 Jul 24 |
1 |
| 10 |
32922037 | CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling. | 2020 |
1 |
| 11 |
30272818 | Microvesicles-mediated communication between endothelial cells modulates, endothelial survival, and angiogenic function via transferring of miR-125a-5p. | 2019 Mar |
1 |
| 12 |
30296564 | TCF21 inhibits proliferation and chemoresistance through the AKT pathway in human gastric cancer. | 2019 Jan 15 |
1 |
| 13 |
31418381 | [Angelica Polysaccharide Resists Platelets Apoptosis Induced by LY294002]. | 2019 Aug |
1 |
| 14 |
29687528 | Nobiletin protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage. | 2018 May |
1 |
| 15 |
29956736 | Reversal of the Warburg effect with DCA in PDGF‑treated human PASMC is potentiated by pyruvate dehydrogenase kinase‑1 inhibition mediated through blocking Akt/GSK‑3β signalling. | 2018 Sep |
2 |
| 16 |
29983082 | Orexin-A protects SH-SY5Y cells against H2O2-induced oxidative damage via the PI3K/MEK1/2/ERK1/2 signaling pathway. | 2018 Jan-Dec |
1 |
| 17 |
30061946 | CCL2 influences the sensitivity of lung cancer A549 cells to docetaxel. | 2018 Jul |
1 |
| 18 |
30259565 | Sodium butyrate ameliorates lipopolysaccharide-induced cow mammary epithelial cells from oxidative stress damage and apoptosis. | 2018 Sep 26 |
1 |
| 19 |
30471224 | Suppression of Apoptosis in Human Umbilical Vein Endothelial Cells (HUVECs) by Klotho Protein is Associated with Reduced Endoplasmic Reticulum Oxidative Stress and Activation of the PI3K/AKT Pathway. | 2018 Nov 24 |
1 |
| 20 |
27817185 | Pharmacologic Inhibition of Autophagy Sensitizes Human Acute Leukemia Jurkat T Cells to Acacetin-Induced Apoptosis. | 2017 Jan 28 |
1 |
| 21 |
28713974 | miRNA-125b regulates apoptosis of human non-small cell lung cancer via the PI3K/Akt/GSK3β signaling pathway. | 2017 Sep |
1 |
| 22 |
28731179 | Clinical significance of miR-138 in patients with malignant melanoma through targeting of PDK1 in the PI3K/AKT autophagy signaling pathway. | 2017 Sep |
1 |
| 23 |
28775672 | Regulatory effects of COL1A1 on apoptosis induced by radiation in cervical cancer cells. | 2017 |
1 |
| 24 |
26919896 | The Src family tyrosine kinases src and yes have differential effects on inflammation-induced apoptosis in human pulmonary microvascular endothelial cells. | 2016 May 1 |
1 |
| 25 |
27018134 | Attenuative role of mangiferin in oxidative stress-mediated liver dysfunction in arsenic-intoxicated murines. | 2016 Sep 10 |
1 |
| 26 |
27392709 | Lp-PLA2 silencing protects against ox-LDL-induced oxidative stress and cell apoptosis via Akt/mTOR signaling pathway in human THP1 macrophages. | 2016 Sep 2 |
1 |
| 27 |
25638174 | Luteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancer. | 2015 Feb 1 |
1 |
| 28 |
26366999 | IL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway. | 2015 |
1 |
| 29 |
24757411 | Fragile histidine triad (FHIT) suppresses proliferation and promotes apoptosis in cholangiocarcinoma cells by blocking PI3K-Akt pathway. | 2014 |
1 |
| 30 |
25344912 | Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway. | 2014 Nov 30 |
1 |
| 31 |
22457005 | TLR3-mediated apoptosis and activation of phosphorylated Akt in the salivary gland epithelial cells of primary Sjögren's syndrome patients. | 2013 Feb |
1 |
| 32 |
23188122 | Extract of Clinopodium chinense inhibits high glucose-induced apoptosis in human umbilical vein endothelial cells. | 2013 Apr |
1 |
| 33 |
23375756 | Tumor necrosis factor-related apoptosis-inducing ligand promotes microvascular endothelial cell hyperpermeability through phosphatidylinositol 3-kinase pathway. | 2013 Apr |
1 |
| 34 |
23420486 | Synergistic lethality of mifepristone and LY294002 in ovarian cancer cells. | 2013 |
1 |
| 35 |
23743572 | Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine. | 2013 Aug |
1 |
| 36 |
23900601 | A novel HDAC inhibitor OBP-801 and a PI3K inhibitor LY294002 synergistically induce apoptosis via the suppression of survivin and XIAP in renal cell carcinoma. | 2013 Oct |
1 |
| 37 |
22994717 | LY294002 induces G0/G1 cell cycle arrest and apoptosis of cancer stem-like cells from human osteosarcoma via down-regulation of PI3K activity. | 2012 |
1 |
| 38 |
21245990 | LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway. | 2011 Jan 14 |
2 |
| 39 |
21300060 | Down-regulation of PKHD1 induces cell apoptosis through PI3K and NF-κB pathways. | 2011 Apr 15 |
1 |
| 40 |
21303966 | Low-level C-reactive protein levels exert cytoprotective actions on human podocytes. | 2011 Aug |
1 |
| 41 |
21370247 | Ghrelin inhibits AGEs-induced apoptosis in human endothelial cells involving ERK1/2 and PI3K/Akt pathways. | 2011 Mar |
1 |
| 42 |
20010439 | Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis. | 2010 Feb |
3 |
| 43 |
19278624 | Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation. | 2009 May |
1 |
| 44 |
19513559 | Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt. | 2009 Jul |
1 |
| 45 |
19738051 | Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target. | 2009 Sep 15 |
1 |
| 46 |
19827268 | Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells. | 2009 |
1 |
| 47 |
18256309 | Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. | 2008 Apr |
1 |
| 48 |
18269934 | IGF-I protects human oral buccal mucosal epithelial cells from sodium nitroprusside-induced apoptosis via PI3-kinase. | 2008 Aug |
1 |
| 49 |
18791828 | Rapid and significant induction of TRAIL-mediated type II cells in apoptosis of primary salivary epithelial cells in primary Sjögren's syndrome. | 2008 Nov |
1 |
| 50 |
17303382 | Hypoxia induces apoptosis of HUVECs in an in vitro capillary model by activating proapoptotic signal p38 through suppression of ERK1/2. | 2007 Jun |
1 |