Protein Name nitric oxide synthase 3
Organism Homo sapiens
Gene ID 4846
Gene Symbol

NOS3

UniProt P29474 (NOS3_HUMAN), A0S0A6 (A0S0A6_HUMAN)
Relationships Total Number of functionally related compound(s) : 1142
Total Number of Articles : 2629
Description

nitric oxide synthase 3

Gene Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

synonyms
  • nitric oxide synthase 3
  • EC-NOS
  • NOS type III
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Properties