Reactive Oxygen Species


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8447 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 635
2 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 608
3 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 568
4 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 511
5 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 490
6 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 484
7 catalase CATA_HUMAN CAT Homo sapiens 847 2305 480
8 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 402
9 NADPH oxidase 4 NOX4_HUMAN NOX4 Homo sapiens 50507 477 390
10 X-linked Kx blood group XK_HUMAN XK Homo sapiens 7504 753 348
11 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 336
12 cytochrome b-245 beta chain CY24B_HUMAN CYBB Homo sapiens 1536 409 332
13 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 332
14 superoxide dismutase 2 SODM_HUMAN SOD2 Homo sapiens 6648 841 325
15 angiotensinogen ANGT_HUMAN AGT Homo sapiens 183 2109 325
16 superoxide dismutase 1 SODC_HUMAN SOD1 Homo sapiens 6647 2118 315
17 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 291
18 insulin INS_HUMAN INS Homo sapiens 3630 7950 283
19 cytochrome b-245, beta polypeptide CY24B_MOUSE Cybb Mus musculus 13058 407 277
20 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 269
21 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 267
22 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 241
23 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 240
24 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 228
25 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 222
26 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 219
27 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 210
28 NLR family pyrin domain containing 3 NLRP3_HUMAN NLRP3 Homo sapiens 114548 1179 205
29 NADPH oxidase 1 NOX1_HUMAN NOX1 Homo sapiens 27035 215 201
30 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 189
31 NADPH oxidase 4 NOX4_MOUSE Nox4 Mus musculus 50490 285 185
32 thioredoxin THIO_HUMAN TXN Homo sapiens 7295 989 183
33 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 179
34 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 166
35 Rac family small GTPase 1 RAC1_HUMAN RAC1 Homo sapiens 5879 884 161
36 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 160
37 synuclein alpha SYUA_HUMAN SNCA Homo sapiens 6622 1780 159
38 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 156
39 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 155
40 NLR family, pyrin domain containing 3 NLRP3_MOUSE Nlrp3 Mus musculus 216799 1325 153
41 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 149
42 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 147
43 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 141
44 mitogen-activated protein kinase 8 MK08_MOUSE Mapk8 Mus musculus 26419 1537 139
45 myeloperoxidase PERM_HUMAN MPO Homo sapiens 4353 1840 135
46 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 133
47 uncoupling protein 2 UCP2_HUMAN UCP2 Homo sapiens 7351 290 131
48 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 129
49 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 128
50 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 121