Reactive Oxygen Species


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8447 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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51 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 121
52 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 119
53 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 117
54 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 115
55 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 112
56 catalase CATA_MOUSE Cat Mus musculus 12359 1084 106
57 cytochrome P450 family 2 subfamily E member 1 CP2E1_HUMAN CYP2E1 Homo sapiens 1571 990 103
58 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 102
59 superoxide dismutase 2, mitochondrial SODM_MOUSE Sod2 Mus musculus 20656 455 102
60 heme oxygenase 1 HMOX1_MOUSE Hmox1 Mus musculus 15368 1339 99
61 formyl peptide receptor 1 FPR1_HUMAN FPR1 Homo sapiens 2357 1382 98
62 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 95
63 NADPH oxidase 1 NOX1_MOUSE Nox1 Mus musculus 237038 159 94
64 sirtuin 1 SIR1_HUMAN SIRT1 Homo sapiens 23411 1253 94
65 NADPH oxidase 4 NOX4_RAT Nox4 Rattus norvegicus 85431 270 91
66 mitogen-activated protein kinase kinase kinase 5 M3K5_HUMAN MAP3K5 Homo sapiens 4217 330 91
67 NFE2 like bZIP transcription factor 2 NF2L2_RAT Nfe2l2 Rattus norvegicus 83619 1416 91
68 uncoupling protein 2 (mitochondrial, proton carrier) UCP2_MOUSE Ucp2 Mus musculus 22228 211 90
69 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 89
70 dual oxidase 2 DUOX2_HUMAN DUOX2 Homo sapiens 50506 135 88
71 NAD(P)H quinone dehydrogenase 1 NQO1_HUMAN NQO1 Homo sapiens 1728 1064 86
72 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 85
73 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 84
74 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 83
75 superoxide dismutase 1, soluble SODC_MOUSE Sod1 Mus musculus 20655 689 82
76 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 82
77 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 80
78 toll like receptor 4 TLR4_HUMAN TLR4 Homo sapiens 7099 1426 79
79 mitogen-activated protein kinase 8 MK08_RAT Mapk8 Rattus norvegicus 116554 1068 79
80 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 78
81 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 78
82 mitogen activated protein kinase 14 Q56A33_RAT Mapk14 Rattus norvegicus 81649 1429 77
83 nitric oxide synthase 2 NOS2_HUMAN NOS2 Homo sapiens 4843 2012 77
84 interleukin 1 alpha IL1A_HUMAN IL1A Homo sapiens 3552 2741 77
85 NADPH oxidase 5 NOX5_HUMAN NOX5 Homo sapiens 79400 102 77
86 xanthine dehydrogenase XDH_HUMAN XDH Homo sapiens 7498 285 74
87 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 73
88 protein kinase AMP-activated catalytic subunit alpha 2 AAPK2_HUMAN PRKAA2 Homo sapiens 5563 919 71
89 sirtuin 3 SIR3_HUMAN SIRT3 Homo sapiens 23410 319 71
90 kelch like ECH associated protein 1 KEAP1_HUMAN KEAP1 Homo sapiens 9817 659 70
91 Rac family small GTPase 1 RAC1_MOUSE Rac1 Mus musculus 19353 323 67
92 neutrophil cytosolic factor 1 NCF1_HUMAN NCF1 Homo sapiens 653361 251 67
93 transient receptor potential cation channel subfamily M member 2 TRPM2_HUMAN TRPM2 Homo sapiens 7226 203 66
94 cytochrome b-245 beta chain Q9ER28_RAT Cybb Rattus norvegicus 66021 259 66
95 nitric oxide synthase 3 NOS3_HUMAN NOS3 Homo sapiens 4846 1142 66
96 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 64
97 xanthine dehydrogenase XDH_MOUSE Xdh Mus musculus 22436 370 64
98 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 63
99 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 63
100 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 63