Reactive Oxygen Species

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







332 Article(s)
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1 34875217 MiR-125b attenuates retinal pigment epithelium oxidative damage via targeting Nrf2/HIF-1α signal pathway. 2022 Jan 1 1
2 35141004 Mitochondrial DHODH regulates hypoxia-inducible factor 1 expression in OTSCC. 2022 6
3 35386720 Cholesterol and HIF-1α: Dangerous Liaisons in Atherosclerosis. 2022 1
4 35629355 The Antileukemic and Anti-Prostatic Effect of Aeroplysinin-1 Is Mediated through ROS-Induced Apoptosis via NOX Activation and Inhibition of HIF-1a Activity. 2022 May 5 1
5 35633910 Sirtuin1 attenuates acute liver failure by reducing reactive oxygen species via hypoxia inducible factor 1α. 2022 May 7 1
6 33393151 Expression of asporin reprograms cancer cells to acquire resistance to oxidative stress. 2021 Mar 1
7 33410354 Feedback of hypoxia-inducible factor-1alpha (HIF-1alpha) transcriptional activity via redox factor-1 (Ref-1) induction by reactive oxygen species (ROS). 2021 Feb 10
8 33510945 HDAC1-mediated deacetylation of HIF1α prevents atherosclerosis progression by promoting miR-224-3p-mediated inhibition of FOSL2. 2021 Mar 5 2
9 33738869 Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase-1 through HIF-1α. 2021 Jun 2
10 33761438 Spleen tyrosine kinase regulates crosstalk of hypoxia-inducible factor-1α and nuclear factor (erythroid-derived2)-like 2 for B cell survival. 2021 Jun 2
11 33771976 CXCR4 promotes B cell viability by the cooperation of nuclear factor (erythroid-derived 2)-like 2 and hypoxia-inducible factor-1α under hypoxic conditions. 2021 Mar 26 1
12 33773069 Antitumor effects of low-dose tipifarnib on the mTOR signaling pathway and reactive oxygen species production in HIF-1α-expressing gastric cancer cells. 2021 May 1
13 33832535 Hypoxia-dependent expression of MAP17 coordinates the Warburg effect to tumor growth in hepatocellular carcinoma. 2021 Apr 8 2
14 33921908 Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic Strategies. 2021 Apr 19 1
15 33955074 Enhanced anti-angiogenic activity of novel melatonin-like agents. 2021 Aug 3
16 33990544 Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer. 2021 May 14 2
17 34008617 An albumin-binding dimeric prodrug nanoparticle with long blood circulation and light-triggered drug release for chemo-photodynamic combination therapy against hypoxia-induced metastasis of lung cancer. 2021 May 18 2
18 34089426 HIF-1α in the Crosstalk Between Reactive Oxygen Species and Autophagy Process: A Review in Multiple Sclerosis. 2021 Jun 5 1
19 34180675 Ultrasmall Barium Titanate Nanoparticles for Highly Efficient Hypoxic Tumor Therapy via Ultrasound Triggered Piezocatalysis and Water Splitting. 2021 Jun 28 1
20 34205678 Transforming Growth Factor-β and Oxidative Stress in Cancer: A Crosstalk in Driving Tumor Transformation. 2021 Jun 21 1
21 34257808 NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma. 2021 2
22 34277453 Comparison of COVID-19 and Lung Cancer via Reactive Oxygen Species Signaling. 2021 3
23 34460078 Hypoxia-induced ROS promotes mitochondrial fission and cisplatin chemosensitivity via HIF-1α/Mff regulation in head and neck squamous cell carcinoma. 2021 Oct 3
24 34512862 HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats. 2021 1
25 34548527 Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism. 2021 Sep 21 2
26 34558885 Diallyl Trisulfide Suppresses High-Glucose-Induced Cardiomyocyte Apoptosis by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1α/Insulin-like Growth Factor Binding Protein 3 Activation. 2021 Oct 6 5
27 34736121 Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro. 2021 Oct 19 2
28 34790659 Mitophagy Protects the Retina Against Anti-Vascular Endothelial Growth Factor Therapy-Driven Hypoxia via Hypoxia-Inducible Factor-1α Signaling. 2021 1
29 34793601 The role of the electron transport chain in immunity. 2021 Dec 2
30 34938777 Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes. 2021 2
31 34992822 Succinate dehydrogenase 5 regulates lung cancer metastasis by reprogramming glucose metabolism. 2021 Nov 2
32 35096971 Accumulated ROS Activates HIF-1α-Induced Glycolysis and Exerts a Protective Effect on Sensory Hair Cells Against Noise-Induced Damage. 2021 2
33 32432042 FtH-Mediated ROS Dysregulation Promotes CXCL12/CXCR4 Axis Activation and EMT-Like Trans-Differentiation in Erythroleukemia K562 Cells. 2020 2
34 32454119 Endosome-triggered ion-releasing nanoparticles as therapeutics to enhance the angiogenic efficacy of human mesenchymal stem cells. 2020 Aug 10 1
35 32515977 Assessing the Effect of Reactive Oxygen Species and Volatile Organic Compound Profiles Coming from Certain Types of Chinese Cooking on the Toxicity of Human Bronchial Epithelial Cells. 2020 Jul 21 1
36 32566089 Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation. 2020 3
37 32585931 Glucose Metabolism and Oxidative Stress in Hepatocellular Carcinoma: Role and Possible Implications in Novel Therapeutic Strategies. 2020 Jun 23 1
38 32596991 Novel evidence for oncogenic piRNA-823 as a promising prognostic biomarker and a potential therapeutic target in colorectal cancer. 2020 Aug 2
39 32719331 HIF-1α regulates cellular metabolism, and Imatinib resistance by targeting phosphogluconate dehydrogenase in gastrointestinal stromal tumors. 2020 Jul 27 4
40 32730232 Hypoxia-inducible factors and obstructive sleep apnea. 2020 Oct 1 3
41 32829253 HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury. 2020 Sep 2
42 32899154 Methylglyoxal-Induced Dysfunction in Brain Endothelial Cells via the Suppression of Akt/HIF-1α Pathway and Activation of Mitophagy Associated with Increased Reactive Oxygen Species. 2020 Sep 3 4
43 33147459 Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma. 2020 Nov 3 1
44 33282113 Hypoxia-Inducible Factor-1: A Potential Target to Treat Acute Lung Injury. 2020 4
45 33293849 Reactive Oxygen Species: Drivers of Physiological and Pathological Processes. 2020 1
46 33553145 Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells. 2020 3
47 30038060 The SLC34A2-ROS-HIF-1-induced up-regulation of EZH2 expression promotes proliferation and chemo-resistance to apoptosis in colorectal cancer. 2019 May 31 6
48 30315766 AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis. 2019 Jan 1
49 30460535 The role of mitochondria in angiogenesis. 2019 Feb 1
50 30569127 Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF. 2019 Feb 1