Reactive Oxygen Species

mitogen-activated protein kinase 8 ; Mus musculus







139 Article(s)
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1 34826588 MAP kinases in regulation of NOX activity stimulated through two types of formyl peptide receptors in murine bone marrow granulocytes. 2022 Feb 1
2 34863682 Repressing c-Jun N-terminal kinase signaling mitigates retinal pigment epithelium degeneration in mice with failure to clear all-trans-retinal. 2022 Jan 1
3 35096269 Silibinin Alleviates Muscle Atrophy Caused by Oxidative Stress Induced by Cisplatin through ERK/FoxO and JNK/FoxO Pathways. 2022 1
4 35453404 Induction of Heme Oxygenase-1 by 15d-Prostaglandin J2 Mediated via a ROS-Dependent Sp1 and AP-1 Cascade Suppresses Lipopolysaccharide-Triggered Interleukin-6 Expression in Mouse Brain Microvascular Endothelial Cells. 2022 Apr 6 1
5 35471608 ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death. 2022 May 4
6 35593352 Tanshinone IIA alleviates the biological characteristics of colorectal cancer via activating the ROS/JNK signaling pathway. 2022 Apr 21 3
7 33184449 Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway. 2021 Aug 1
8 33187846 Tetrachlorobenzoquinone exhibits immunotoxicity by inducing neutrophil extracellular traps through a mechanism involving ROS-JNK-NOX2 positive feedback loop. 2021 Jan 1 5
9 33401054 Induction of apoptosis by Shikonin through ROS-mediated intrinsic and extrinsic apoptotic pathways in primary effusion lymphoma. 2021 Mar 2
10 33676788 Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis. 2021 Apr 1
11 33690262 Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway. 2021 Mar 9 1
12 33716741 Fisetin Rescues the Mice Brains Against D-Galactose-Induced Oxidative Stress, Neuroinflammation and Memory Impairment. 2021 1
13 33823244 Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury. 2021 May 20 1
14 34027642 Effect and Mechanism Study of Sodium Houttuyfonate on Ventilator-Induced Lung Injury by Inhibiting ROS and Inflammation. 2021 Jun 1
15 34048572 Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response. 2021 Jun 4 2
16 34088892 NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving. 2021 Jun 4 3
17 34331779 Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis. 2021 Dec 2
18 32106375 Therapeutic benefits of apocynin in mice with lipopolysaccharide/D-galactosamine-induced acute liver injury via suppression of the late stage pro-apoptotic AMPK/JNK pathway. 2020 May 1
19 32192500 Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury. 2020 Mar 20 1
20 32214827 Polyphyllin VI Induces Apoptosis and Autophagy via Reactive Oxygen Species Mediated JNK and P38 Activation in Glioma. 2020 2
21 32237051 SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation. 2020 May 1
22 32265302 Activation of JNK signaling promotes all-trans-retinal-induced photoreceptor apoptosis in mice. 2020 May 15 4
23 32330587 Reactive oxygen species (ROS) generation as an underlying mechanism of inorganic phosphate (Pi)-induced mineralization of osteogenic cells. 2020 Jun 1
24 32650472 Mojabanchromanol Isolated from Sargassum horneri Attenuates Particulate Matter Induced Inflammatory Responses via Suppressing TLR2/4/7-MAPK Signaling in MLE-12 Cells. 2020 Jul 8 1
25 33037139 Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis. 2020 Nov 15 1
26 33052927 Carnosine suppresses neuronal cell death and inflammation induced by 6-hydroxydopamine in an in vitro model of Parkinson's disease. 2020 1
27 33124187 NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β-cells for protection. 2020 Dec 7
28 30706943 Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway. 2019 Apr 1
29 30760405 TRAF1 meditates lipopolysaccharide-induced acute lung injury by up regulating JNK activation. 2019 Mar 26 1
30 30796935 Cadmium-induced apoptosis through reactive oxygen species-mediated mitochondrial oxidative stress and the JNK signaling pathway in TM3 cells, a model of mouse Leydig cells. 2019 Apr 1 6
31 31072360 Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells. 2019 May 9 1
32 31229567 Maduramicin induces apoptosis through ROS-PP5-JNK pathway in skeletal myoblast cells and muscle tissue. 2019 Aug 1 3
33 31326607 l-Serine protects mouse hippocampal neuronal HT22 cells against oxidative stress-mediated mitochondrial damage and apoptotic cell death. 2019 Sep 1
34 27957682 Dissociation of JNK Activation from Elevated Levels of Reactive Oxygen Species, Cytochrome c Release, and Cell Death in NGF-Deprived Sympathetic Neurons. 2018 Jan 4
35 28369910 Acute ethanol exposure-induced autophagy-mediated cardiac injury via activation of the ROS-JNK-Bcl-2 pathway. 2018 Feb 2
36 29022274 Midazolam prevents motor neuronal death from oxidative stress attack mediated by JNK-ERK pathway. 2018 Jan 1
37 29577871 Long noncoding RNA MALAT1 regulates generation of reactive oxygen species and the insulin responses in male mice. 2018 Jun 2
38 29624862 The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells. 2018 Jun 1
39 29778464 Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice. 2018 Aug 1 3
40 29849867 Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes. 2018 1
41 29932926 Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species. 2018 Aug 15 1
42 30153650 Over-expression of a cardiac-specific human dopamine D5 receptor mutation in mice causes a dilated cardiomyopathy through ROS over-generation by NADPH oxidase activation and Nrf2 degradation. 2018 Oct 1
43 30223653 Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism. 2018 Nov 5 2
44 30237126 Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells. 2018 Oct 5
45 30290020 Nilotinib induction of melanogenesis via reactive oxygen species-dependent JNK activation in B16F0 mouse melanoma cells. 2018 Dec 2
46 30340823 Proviral insertion in murine lymphomas 2 promotes stomach cancer progression by regulating apoptosis via reactive oxygen species-triggered endoplasmic reticulum stress. 2018 Nov 17 4
47 30348527 Inhibition of TRAF3 expression alleviates cardiac ischemia reperfusion (IR) injury: A mechanism involving in apoptosis, inflammation and oxidative stress. 2018 Nov 17 3
48 30425486 Immunotoxicity of titanium dioxide nanoparticles via simultaneous induction of apoptosis and multiple toll-like receptors signaling through ROS-dependent SAPK/JNK and p38 MAPK activation. 2018 1
49 28000869 Advanced oxidation protein products induce apoptosis, and upregulate sclerostin and RANKL expression, in osteocytic MLO-Y4 cells via JNK/p38 MAPK activation. 2017 Feb 4
50 28086233 A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma. 2017 Feb 21 3