Reactive Oxygen Species

caspase 3 ; Homo sapiens







228 Article(s)
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1 34989943 A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol. 2022 Mar 2
2 35053370 Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways. 2022 Jan 12 2
3 35063650 Bim- and Bax-mediated mitochondrial pathway dominates abivertinib-induced apoptosis and ferroptosis. 2022 Feb 20 1
4 35085590 Crocin induces ROS-mediated papillary thyroid cancer cell apoptosis by modulating the miR-34a-5p/PTPN4 axis in vitro. 2022 Feb 15 1
5 35291604 PI3K Inhibition Sensitize the Cisplatin-resistant Human Ovarian Cancer Cell OVCAR3 by Induction of Oxidative Stress. 2022 Jan 1
6 35296739 Insight into redox regulation of apoptosis in cancer cells with multiparametric live-cell microscopy. 2022 Mar 16 1
7 35315184 Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells. 2022 Mar 21 1
8 35335178 Protective Effect of Amber Extract on Human Dopaminergic Cells against 6-Hydroxydopamine-Induced Neurotoxicity. 2022 Mar 10 1
9 35422087 SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells. 2022 Apr 14 2
10 35436022 Quercetin attenuates the proliferation of arsenic-related lung cancer cells via a caspase-dependent DNA damage signaling. 2022 Jul 1
11 35458727 Light-Activated Monomethyl Auristatin E Prodrug Nanoparticles for Combinational Photo-Chemotherapy of Pancreatic Cancer. 2022 Apr 14 2
12 35620928 Design of Bio-Graphene-Based Multifunctional Nanocomposites Exhibits Intracellular Drug Delivery in Cervical Cancer Treatment. 2022 Jun 20 2
13 33262826 Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum. 2021 Jan 2
14 33515385 Apocynin ameliorates NADPH oxidase 4 (NOX4) induced oxidative damage in the hypoxic human retinal Müller cells and diabetic rat retina. 2021 May 1
15 33549076 Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells. 2021 Feb 6 1
16 33558527 Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells. 2021 Feb 8 4
17 33589596 Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity. 2021 Feb 15 1
18 33711532 Modulation of the triggered apoptosis by nano emodin transfersome-mediated sonodynamic therapy on head and neck squamous cell carcinoma cell lines. 2021 Jun 1
19 33918814 Novel Semi-Synthetic Cu (II)-Cardamonin Complex Exerts Potent Anticancer Activity against Triple-Negative Breast and Pancreatic Cancer Cells via Inhibition of the Akt Signaling Pathway. 2021 Apr 9 2
20 33953844 Piperlongumine promotes death of retinoblastoma cancer cells. 2021 Apr 27 1
21 34038094 In Situ Imaging of Cellular Reactive Oxygen Species and Caspase-3 Activity Using a Multifunctional Theranostic Probe for Cancer Diagnosis and Therapy. 2021 Jun 8 3
22 34216806 Sunitinib with photoirradiation-mediated reactive oxygen species generation induces apoptosis of renal cell carcinoma cells. 2021 Sep 2
23 34249731 A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells. 2021 2
24 34254800 Evaluating Peptides of Picrorhiza kurroa and Their Inhibitory Potential against ACE, DPP-IV, and Oxidative Stress. 2021 Aug 6 1
25 34305590 Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells. 2021 1
26 34492530 Photodynamic therapy of prostate cancer using porphyrinic formulations. 2021 Oct 2
27 34549778 Chlorothalonil induces the intestinal epithelial barrier dysfunction in Caco-2 cell-based in vitro monolayer model by activating MAPK pathway. 2021 Nov 10 1
28 34928029 An Efficient Carbon-Based Drug Delivery System for Cancer Therapy through the Nucleus Targeting and Mitochondria Mediated Apoptotic Pathway. 2021 Dec 2
29 31874443 Berberine associated photodynamic therapy promotes autophagy and apoptosis via ROS generation in renal carcinoma cells. 2020 Mar 2
30 32695909 Novel 3,4-diarylpyrazole as prospective anti-cancerous agents. 2020 Jul 1
31 32700751 Sensitivity of allyl isothiocyanate to induce apoptosis via ER stress and the mitochondrial pathway upon ROS production in colorectal adenocarcinoma cells. 2020 Oct 2
32 32827965 Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6. 2020 Dec 1 2
33 32956875 Synthesis and biological evaluation of β-ionone oriented proapoptosis agents by enhancing the ROS generation. 2020 Nov 2
34 32961495 Clusterin alleviates Cr(VI)-induced mitochondrial apoptosis in L02 hepatocytes via inhibition of Ca2+-ROS-Drp1-mitochondrial fission axis. 2020 Dec 1 2
35 33099948 Anticancer activity of Voacangine against human oral cancer cells is due to G2/M cell cycle arrest, ROS-mediated cell death and inhibition of PI3K/AKT signalling pathway. 2020 Jul-Aug 1
36 33178287 Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from Higher-Risk MDS Patients by Regulating the ROS-Related Wnt/β-Catenin Pathway. 2020 2
37 30365122 Vorinostat enhances gefitinib‑induced cell death through reactive oxygen species‑dependent cleavage of HSP90 and its clients in non‑small cell lung cancer with the EGFR mutation. 2019 Jan 2
38 30431086 Activation of the Notch‑Nox4‑reactive oxygen species signaling pathway induces cell death in high glucose‑treated human retinal endothelial cells. 2019 Jan 1
39 30452899 Oenothein B inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-κB signaling pathway. 2019 Jan 25 1
40 30500452 A novel mechanism of Gamma-aminobutyric acid (GABA) protecting human umbilical vein endothelial cells (HUVECs) against H2O2-induced oxidative injury. 2019 Mar 1
41 30717391 Loliolide Presents Antiapoptosis and Antiscratching Effects in Human Keratinocytes. 2019 Feb 2 1
42 30728888 Hypoxia-Activated PI3K/Akt Inhibits Oxidative Stress via the Regulation of Reactive Oxygen Species in Human Dental Pulp Cells. 2019 1
43 30984335 ROS Induced by KillerRed Targeting Mitochondria (mtKR) Enhances Apoptosis Caused by Radiation via Cyt c/Caspase-3 Pathway. 2019 1
44 31083557 Antioxidant and Anti-Apoptotic Properties of Oat Bran Protein Hydrolysates in Stressed Hepatic Cells. 2019 May 11 2
45 31091501 Spermatogenesis disorder caused by T-2 toxin is associated with germ cell apoptosis mediated by oxidative stress. 2019 Aug 1
46 31104320 IL-8 protects prostate cancer cells from GSK-3β-induced oxidative stress by activating the mTOR signaling pathway. 2019 Jul 2
47 31139404 Apoptotic effects of hsian-tsao (Mesona procumbens Hemsley) on hepatic stellate cells mediated by reactive oxygen species and ERK, JNK, and caspase-3 pathways. 2019 May 1
48 31249651 Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway. 2019 1
49 31298468 Thymoquinone suppresses the proliferation of renal cell carcinoma cells via reactive oxygen species-induced apoptosis and reduces cell stemness. 2019 Nov 1
50 31371783 Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation. 2019 Nov 4