Protein Name myeloperoxidase
Organism Homo sapiens
Gene ID 4353
Gene Symbol


UniProt P05164 (PERM_HUMAN)
Relationships Total Number of functionally related compound(s) : 1840
Total Number of Articles : 3047


Gene Summary

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

  • myeloperoxidase
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