Protein Name | myeloperoxidase |
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Organism | Homo sapiens |
Gene ID | 4353 |
Gene Symbol | MPO |
UniProt | P05164 (PERM_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
1840
Total Number of Articles : 3047 |
Description |
myeloperoxidase |
Gene Summary |
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] |
synonyms |
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Properties | |