Reactive Oxygen Species

BCL2 associated X, apoptosis regulator ; Homo sapiens







155 Article(s)
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1 34785775 Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo. 2022 Jan 3
2 35063650 Bim- and Bax-mediated mitochondrial pathway dominates abivertinib-induced apoptosis and ferroptosis. 2022 Feb 20 1
3 35093886 BAX But Not BCL2 Is Necessary for Apoptosis in Neuroblastoma Cells Treated With Casiopeína® IIIia. 2022 Feb 1
4 35202708 Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H+] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes. 2022 Mar 15 1
5 35406117 Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. 2022 Apr 4 1
6 35584569 BAP1 phosphorylation-mediated Sp1 stabilization plays a critical role in cathepsin K inhibition-induced C-terminal p53-dependent Bax upregulation. 2022 Jul 1
7 33470993 Cu(I) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action. 2021 Feb 9 2
8 33520087 Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis. 2021 1
9 33545873 Vitamin-B12-conjugated PLGA-PEG nanoparticles incorporating miR-532-3p induce mitochondrial damage by targeting apoptosis repressor with caspase recruitment domain (ARC) on CD320-overexpressed gastric cancer. 2021 Jan 2
10 34305590 Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells. 2021 1
11 34439474 Garcinia cambogia Ameliorates Non-Alcoholic Fatty Liver Disease by Inhibiting Oxidative Stress-Mediated Steatosis and Apoptosis through NRF2-ARE Activation. 2021 Jul 29 1
12 31995555 Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. 2020 1
13 32103904 Hydrogen Sulfide Protects Against High Glucose-Induced Human Umbilical Vein Endothelial Cell Injury Through Activating PI3K/Akt/eNOS Pathway. 2020 1
14 32560521 Isosamidin from Peucedanum japonicum Roots Prevents Methylglyoxal-Induced Glucotoxicity in Human Umbilical Vein Endothelial Cells via Suppression of ROS-Mediated Bax/Bcl-2. 2020 Jun 17 1
15 32653697 New manganese(II), iron(II), cobalt(II), nickel(II) and copper(II) saccharinate complexes of 2,6-bis(2-benzimidazolyl)pyridine as potential anticancer agents. 2020 Sep 15 1
16 32708163 Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink. 2020 Jul 21 3
17 32878253 Interactions of Zinc Oxide Nanostructures with Mammalian Cells: Cytotoxicity and Photocatalytic Toxicity. 2020 Aug 31 2
18 32879623 Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway. 2020 2
19 32956875 Synthesis and biological evaluation of β-ionone oriented proapoptosis agents by enhancing the ROS generation. 2020 Nov 2
20 33053856 GPR4 Knockout Improves the Neurotoxin-Induced, Caspase-Dependent Mitochondrial Apoptosis of the Dopaminergic Neuronal Cell. 2020 Oct 12 1
21 33099948 Anticancer activity of Voacangine against human oral cancer cells is due to G2/M cell cycle arrest, ROS-mediated cell death and inhibition of PI3K/AKT signalling pathway. 2020 Jul-Aug 1
22 30588027 Methotrexate-induced apoptosis in human ovarian adenocarcinoma SKOV-3 cells via ROS-mediated bax/bcl-2-cyt-c release cascading. 2019 1
23 31091501 Spermatogenesis disorder caused by T-2 toxin is associated with germ cell apoptosis mediated by oxidative stress. 2019 Aug 1
24 31249651 Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway. 2019 2
25 31752383 Acetylshikonin Sensitizes Hepatocellular Carcinoma Cells to Apoptosis through ROS-Mediated Caspase Activation. 2019 Nov 19 1
26 29215703 Design, synthesis, and characterization of α, β-unsaturated carboxylic acid, and its urea based derivatives that explores novel epigenetic modulators in human non-small cell lung cancer A549 cell line. 2018 Jul 2
27 29217266 Auriculasin-induced ROS causes prostate cancer cell death via induction of apoptosis. 2018 Jan 2
28 29310425 Treatment with Phytoestrogens Reversed Triclosan and Bisphenol A-Induced Anti-Apoptosis in Breast Cancer Cells. 2018 Sep 1 1
29 29433671 Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells. 2018 Jan 15 1
30 29545865 Protective effect and molecular mechanism of liquiritin on oxybuprocaine-induced apoptosis of human corneal endothelial cells. 2018 Apr 2
31 29596889 Pro-apoptotic Bax promotes mesenchymal-epithelial transition by binding to respiratory complex-I and antagonizing the malignant actions of pro-survival Bcl-2 proteins. 2018 Jun 28 1
32 29658330 Comparative cytotoxicity and apoptotic pathways induced by nanosilver in human liver HepG2 and L02 cells. 2018 Dec 1
33 29725496 Melatonin Inhibits Reactive Oxygen Species-Driven Proliferation, Epithelial-Mesenchymal Transition, and Vasculogenic Mimicry in Oral Cancer. 2018 1
34 30204479 Bixin Triggers Apoptosis of Human Hep3B Hepatocellular Carcinoma Cells: An Insight to Molecular and IN SILICO Approach. 2018 Aug-Sep 1
35 30287942 Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis. 2018 Dec 1
36 30417780 Neuroprotection with the Endozepine Octadecaneuropeptide, ODN. 2018 1
37 30542399 The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients. 2018 Dec 1
38 28000873 Salvianolic acid B reverses multidrug resistance in HCT‑8/VCR human colorectal cancer cells by increasing ROS levels. 2017 Feb 2
39 28119491 Reactive Oxygen Species-Mediated Synergism of Fenretinide and Romidepsin in Preclinical Models of T-cell Lymphoid Malignancies. 2017 Apr 2
40 28151485 Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. 2017 Feb 2 1
41 28213497 Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. 2017 Mar 7 1
42 28323898 Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells. 2017 2
43 28412728 Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells. 2017 Apr 18 1
44 28443465 Bauerenol, a triterpenoid from Indian Suregada angustifolia: Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. 2017 Apr 1
45 28498435 Plumbagin enhances TRAIL-induced apoptosis of human leukemic Kasumi‑1 cells through upregulation of TRAIL death receptor expression, activation of caspase-8 and inhibition of cFLIP. 2017 Jun 1
46 28558327 d-Alanine 2, Leucine 5 Enkephaline (DADLE)-mediated DOR activation augments human hUCB-BFs viability subjected to oxidative stress via attenuation of the UPR. 2017 Jul 1
47 28642847 Heat-Labile Enterotoxin-Induced PERK-CHOP Pathway Activation Causes Intestinal Epithelial Cell Apoptosis. 2017 2
48 28714389 A Peptide Based Pro-Drug Ameliorates Amyloid-β Induced Neuronal Apoptosis in In Vitro SH-SY5Y Cells. 2017 1
49 28777796 Isoalantolactone induces intrinsic apoptosis through p53 signaling pathway in human lung squamous carcinoma cells. 2017 1
50 29033852 Activation of Casein Kinase II by Gallic Acid Induces BIK-BAX/BAK-Mediated ER Ca++-ROS-Dependent Apoptosis of Human Oral Cancer Cells. 2017 2