Reactive Oxygen Species

NLR family, pyrin domain containing 3 ; Mus musculus







153 Article(s)
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1 34718095 Aurantio-obtusin induces hepatotoxicity through activation of NLRP3 inflammasome signaling. 2022 Jan 1 1
2 34740771 Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity. 2022 Mar 1 1
3 34984798 Lithium intoxication induced pyroptosis via ROS/NF-κB/NLRP3 inflammasome regulatory networks in kidney of mice. 2022 Apr 1
4 35000152 Study of the Involvement of the P2Y12 Receptor in Chronic Itching in Type 2 Diabetes Mellitus. 2022 Mar 1
5 35008006 C1q/tumour necrosis factor-related protein-9 aggravates lipopolysaccharide-induced inflammation via promoting NLRP3 inflammasome activation. 2022 Mar 2
6 35124564 Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury by exerting an anti-pyroptotic effect via the miR-139-5p/FoxO1/Keap1/Nrf2 axis. 2022 Apr 1
7 35338958 ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model. 2022 Jun 3
8 35344845 PM2.5 induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis. 2022 May 2
9 35379787 ATP6AP2 knockdown in cardiomyocyte deteriorates heart function via compromising autophagic flux and NLRP3 inflammasome activation. 2022 Apr 4 1
10 35524333 AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model. 2022 May 6 4
11 35545588 [The role of ROS/TXNIP/NLRP3 pathway in the skin injury of trichloroethylene sensitized mice]. 2022 Apr 20 1
12 35569032 Ipriflavone suppresses NLRP3 inflammasome activation in host response to biomaterials and promotes early bone healing. 2022 May 15 4
13 32814473 Irisin alleviates LPS-induced liver injury and inflammation through inhibition of NLRP3 inflammasome and NF-κB signaling. 2021 Jun 1
14 32949934 Airborne particulate matter (PM2.5) triggers cornea inflammation and pyroptosis via NLRP3 activation. 2021 Jan 1 1
15 33097834 USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy. 2021 Oct 1
16 33232925 Uric acid aggravates myocardial ischemia-reperfusion injury via ROS/NLRP3 pyroptosis pathway. 2021 Jan 1
17 33268842 Exercise suppresses NLRP3 inflammasome activation in mice with diet-induced NASH: a plausible role of adropin. 2021 Mar 2
18 33352229 Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases. 2021 Feb 1
19 33717152 NLRP3 Deficiency Protects Against Intermittent Hypoxia-Induced Neuroinflammation and Mitochondrial ROS by Promoting the PINK1-Parkin Pathway of Mitophagy in a Murine Model of Sleep Apnea. 2021 1
20 33770730 Oridonin ameliorates noise-induced hearing loss by blocking NLRP3 - NEK7 mediated inflammasome activation. 2021 Jun 2
21 33830232 1'-Acetoxychavicol acetate inhibits NLRP3-dependent inflammasome activation via mitochondrial ROS suppression. 2021 Jun 18 1
22 34030116 Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes. 2021 Jul 3
23 34102208 N-acetylcysteine alleviates ocular surface damage in STZ-induced diabetic mice by inhibiting the ROS/NLRP3/Caspase-1/IL-1β signaling pathway. 2021 Aug 1
24 34173703 PM2.5 induces endothelial dysfunction via activating NLRP3 inflammasome. 2021 Sep 2
25 34353430 Anti-inflammatory effects of N-cyclooctyl-5-methylthiazol-2-amine hydrobromide on lipopolysaccharide-induced inflammatory response through attenuation of NLRP3 activation in microglial cells. 2021 Nov 2
26 34480147 Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages. 2021 Oct 3
27 34511904 Elemene Nanoemulsion Inhibits Metastasis of Breast Cancer by ROS Scavenging. 2021 1
28 34512861 XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway. 2021 1
29 34628369 Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome. 2021 Oct 9 1
30 34789781 The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages. 2021 Nov 17 2
31 34810128 Extracellular citrate serves as a DAMP to activate macrophages and promote LPS-induced lung injury in mice. 2021 Dec 2
32 34820388 GSDMD Mediates LPS-Induced Septic Myocardial Dysfunction by Regulating ROS-dependent NLRP3 Inflammasome Activation. 2021 3
33 34829577 S1P/S1P2 Signaling Axis Regulates Both NLRP3 Upregulation and NLRP3 Inflammasome Activation in Macrophages Primed with Lipopolysaccharide. 2021 Oct 27 3
34 32081748 Geniposide protects against sepsis-induced myocardial dysfunction through AMPKα-dependent pathway. 2020 May 20 1
35 32192500 Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury. 2020 Mar 20 1
36 32194416 Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis. 2020 1
37 32246016 Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation. 2020 Apr 3 2
38 32407725 A prodrug of epigallocatechin-3-gallate alleviates high glucose-induced pro-angiogenic factor production by inhibiting the ROS/TXNIP/NLRP3 inflammasome axis in retinal Müller cells. 2020 Jul 2
39 32435622 Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome. 2020 2
40 32452554 Epoxyeicosatrienoic acids inhibit the activation of NLRP3 inflammasome in murine macrophages. 2020 Dec 1
41 32454054 NLRP3 inflammasome-dependent pyroptosis and apoptosis in hippocampus neurons mediates depressive-like behavior in diabetic mice. 2020 Aug 5 2
42 32647664 Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury. 2020 Jun 2
43 32674019 Oxidative stress activates the TRPM2-Ca2+-NLRP3 axis to promote PM2.5-induced lung injury of mice. 2020 Oct 3
44 32705396 Melatonin Attenuates Thrombin-induced Inflammation in BV2 Cells and Then Protects HT22 Cells from Apoptosis. 2020 Oct 2
45 32829380 ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway. 2020 Aug 22 1
46 32849566 Supraphysiological Levels of Testosterone Induce Vascular Dysfunction via Activation of the NLRP3 Inflammasome. 2020 1
47 32850832 Nucleotide-Binding Oligomerization Domain-Like Receptor 3 Deficiency Attenuated Isoproterenol-Induced Cardiac Fibrosis via Reactive Oxygen Species/High Mobility Group Box 1 Protein Axis. 2020 2
48 32891159 Deficiency of the microglial Hv1 proton channel attenuates neuronal pyroptosis and inhibits inflammatory reaction after spinal cord injury. 2020 Sep 5 3
49 32891167 ROS-mediated NLRP3 inflammasome activation participates in the response against Neospora caninum infection. 2020 Sep 5 7
50 32900490 Glycyrrhetinic acid alleviates acute lung injury by PI3K/AKT suppressing macrophagic Nlrp3 inflammasome activation. 2020 Nov 19 1