Reactive Oxygen Species

uncoupling protein 2 ; Homo sapiens







131 Article(s)
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1 35091061 T3-induced enhancement of mitochondrial Ca2+ uptake as a boost for mitochondrial metabolism. 2022 Mar 2
2 35091238 Uncoupling proteins as a therapeutic target for the development of new era drugs against neurodegenerative disorder. 2022 Mar 1
3 33763373 UCP2 as a Potential Biomarker for Adjunctive Metabolic Therapies in Tumor Management. 2021 2
4 33879866 Ucp2-dependent microglia-neuronal coupling controls ventral hippocampal circuit function and anxiety-like behavior. 2021 Jul 3
5 34439417 Study of the Antioxidant Effects of Coffee Phenolic Metabolites on C6 Glioma Cells Exposed to Diesel Exhaust Particles. 2021 Jul 23 2
6 34710532 Neuroprotection of retinal cells by Caffeic Acid Phenylethyl Ester(CAPE) is mediated by mitochondrial uncoupling protein UCP2. 2021 Dec 1
7 31479096 -866G/A and Ins/Del polymorphisms in the UCP2 gene and diabetic kidney disease: case-control study and meta-analysis. 2020 4
8 31862780 Reactive Oxygen Species Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3. 2020 Mar 1 2
9 32190174 Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species. 2020 2
10 32425675 Uncoupling protein-2 regulates M1 macrophage infiltration of gingiva with periodontitis. 2020 4
11 32492982 Uncoupling Protein 2 as genetic risk factor for systemic lupus erythematosus: association with malondialdehyde levels and intima media thickness. 2020 Dec 1
12 33162463 Factors affecting expression and transcription of uncoupling protein 2 gene. 2020 Dec 26 1
13 33463495 [Uncoupling protein 2 overexpression alleviates sepsis-induced myocardial injury via inhibiting reactive oxygen species production and inflammation]. 2020 Nov 6
14 30910560 The -866G/A polymorphism in the promoter of the UCP2 gene is associated with risk for type 2 diabetes and with decreased insulin levels. 2019 Jun 15 2
15 31071510 UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production. 2019 Jul 9
16 31218541 The A allele of the UCP2 -866G/A polymorphism changes UCP2 promoter activity in HUVECs treated with high glucose. 2019 Oct 4
17 31249597 MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney Disease. 2019 4
18 31341797 Down regulation of UCP2 expression in retinal pigment epithelium cells under oxidative stress: an in vitro study. 2019 3
19 29859845 Mitochondrial uncoupling, ROS generation and cardioprotection. 2018 Sep 1
20 29861658 Effects of 18β-Glycyrrhetinic Acid on Fungal Protease-Induced Airway Inflammatory Responses. 2018 2
21 29887950 Overexpressed UCP2 regulates mitochondrial flashes and reverses lipopolysaccharide-induced cardiomyocytes injury. 2018 2
22 29928365 Expression of UCP2 is associated with sensitivity to platinum-based chemotherapy for ovarian serous carcinoma. 2018 Jun 4
23 30007886 TGF-β/SMAD4 mediated UCP2 downregulation contributes to Aspergillus protease-induced inflammation in primary bronchial epithelial cells. 2018 Sep 2
24 30116205 Uncoupling Protein 2 in Cardiovascular Health and Disease. 2018 3
25 30160798 Genipin induces cell death via intrinsic apoptosis pathways in human glioblastoma cells. 2018 Aug 30 1
26 30355916 UCP2 Mitigates the Loss of Human Spermatozoa Motility by Promoting mROS Elimination. 2018 1
27 30538804 β3-Adrenoreceptors Control Mitochondrial Dormancy in Melanoma and Embryonic Stem Cells. 2018 1
28 28042952 Uncoupling protein 2 downregulation by hypoxia through repression of peroxisome proliferator-activated receptor γ promotes chemoresistance of non-small cell lung cancer. 2017 Jan 31 1
29 28089824 Mitochondrial Uncoupling Protein 2 in human cumulus cells is associated with regulating autophagy and apoptosis, maintaining gap junction integrity and progesterone synthesis. 2017 Mar 5 4
30 28483672 Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species. 2017 Jul 3
31 28546450 Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling. 2017 Jul 1
32 28574619 UCP2 upregulation promotes PLCγ-1 signaling during skin cell transformation. 2017 Oct 5
33 28693257 UCP2 expression may represent a predictive marker of neoadjuvant chemotherapy effectiveness for locally advanced uterine cervical cancer. 2017 Jul 5
34 28737710 Cytoprotective Effect of the UCP2-SIRT3 Signaling Pathway by Decreasing Mitochondrial Oxidative Stress on Cerebral Ischemia-Reperfusion Injury. 2017 Jul 24 2
35 28969026 Increasing UCP2 expression and decreasing NOX1/4 expression maintain chondrocyte phenotype by reducing reactive oxygen species production. 2017 Sep 8 5
36 29043564 The UCP2-866G/A Polymorphism Could be Considered as a Genetic Marker of Different Functional Prognosis in Ischemic Stroke After Recanalization. 2017 Dec 2
37 26771154 Cytoprotective Effects of Oleanolic Acid in Human Umbilical Vascular Endothelial Cells is Mediated Via UCP2/ROS/Cytochrome C/AIF Pathway. 2016 Apr 1
38 26771380 The Hydroxyl at Position C1 of Genipin Is the Active Inhibitory Group that Affects Mitochondrial Uncoupling Protein 2 in Panc-1 Cells. 2016 2
39 26846204 Overexpression of uncoupling protein 2 inhibits the high glucose-induced apoptosis of human umbilical vein endothelial cells. 2016 Mar 2
40 26919426 UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness. 2016 Feb 25 2
41 27128320 Glucocorticoids Suppress Mitochondrial Oxidant Production via Upregulation of Uncoupling Protein 2 in Hyperglycemic Endothelial Cells. 2016 1
42 27271549 Uncoupling protein 2 regulates metabolic reprogramming and fate of antigen-stimulated CD8+ T cells. 2016 Jul 1
43 27429587 A Mechanism for the Temporal Potentiation of Genipin to the Cytotoxicity of Cisplatin in Colon Cancer Cells. 2016 1
44 27451963 Molecular mechanism of (18)F-FDG uptake reduction induced by genipin in T47D cancer cell and role of uncoupling protein-2 in cancer cell glucose metabolism. 2016 Oct 1
45 27651753 Uncoupling protein 2 in the glial response to stress: implications for neuroprotection. 2016 Aug 3
46 25251374 UCP2-related mitochondrial pathway participates in oroxylin A-induced apoptosis in human colon cancer cells. 2015 May 5
47 25351290 The UCP2 -866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis. 2015 May 2
48 26123077 Genipin suppresses NLRP3 inflammasome activation through uncoupling protein-2. 2015 Sep 2
49 26173855 The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses. 2015 Oct 2
50 26181366 Uncoupling protein 2 mediates resistance to gemcitabine-induced apoptosis in hepatocellular carcinoma cell lines. 2015 Jun 16 4