Reactive Oxygen Species

NADPH oxidase 4 ; Homo sapiens







390 Article(s)
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1 34922273 Implication of type 4 NADPH oxidase (NOX4) in tauopathy. 2022 Feb 3
2 35075615 Impairment of Decidualization of Endometrial Stromal Cells by hsa-miR-375 Through NOX4 Targeting. 2022 Jan 24 1
3 35090586 Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy. 2022 Feb 8 3
4 35124000 Glucagon-like peptide-1 receptor activation by liraglutide promotes breast cancer through NOX4/ROS/VEGF pathway. 2022 Apr 1 1
5 35140544 Poldip2/Nox4 Mediates Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Lung Epithelial Cells. 2022 4
6 35203105 NOX4 regulates TGFβ-induced proliferation and self-renewal in glioblastoma stem cells. 2022 May 2
7 35377824 Hypoxia induces proliferation via NOX4-Mediated oxidative stress and TGF-β3 signaling in uterine leiomyoma cells. 2022 Feb 1
8 35386222 Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS. 2022 2
9 35606794 NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway. 2022 May 23 4
10 33116250 β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of NOX4. 2021 Jul 2
11 33158991 Adipose-specific BMP and activin membrane-bound inhibitor (BAMBI) deletion promotes adipogenesis by accelerating ROS production. 2021 Jan-Jun 1
12 33276949 Protective effect of carnosine on hydrogen peroxide-induced oxidative stress in human kidney tubular epithelial cells. 2021 Jan 1 1
13 33279617 NOD1 activation induces oxidative stress via NOX1/4 in adipocytes. 2021 Jan 1
14 33325804 Profibrotic epithelial TGF-β1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN. 2021 Mar 1 1
15 33504419 [Inhibition of Wnt/β-catenin signal and NOX4 impairs repair of silica-induced lung epithelial cell injury]. 2021 Feb 1
16 33515385 Apocynin ameliorates NADPH oxidase 4 (NOX4) induced oxidative damage in the hypoxic human retinal Müller cells and diabetic rat retina. 2021 May 4
17 33559185 Blockade of mTORC1-NOX signaling pathway inhibits TGF-β1-mediated senescence-like structural alterations of the retinal pigment epithelium. 2021 Mar 1
18 33774476 NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases. 2021 May 3
19 33824697 NOX4-Derived ROS Promotes Collagen I Deposition in Bronchial Smooth Muscle Cells by Activating Noncanonical p38MAPK/Akt-Mediated TGF-β Signaling. 2021 5
20 33857626 Sodium fluoride activates the extrinsic apoptosis via regulating NOX4/ROS-mediated p53/DR5 signaling pathway in lung cells both in vitro and in vivo. 2021 Jun 8
21 33916948 Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto's Thyroiditis. 2021 Apr 7 1
22 33982799 NOXA-mediated degradation of MCL1 and BCL2L1 causes apoptosis of daunorubicin-treated human acute myeloid leukemia cells. 2021 Nov 1
23 34008419 Silver nanoparticles induce apoptosis via NOX4-derived mitochondrial reactive oxygen species and endoplasmic reticulum stress in colorectal cancer cells. 2021 Jul 1
24 34176291 DRD4 (Dopamine D4 Receptor) Mitigate Abdominal Aortic Aneurysm via Decreasing P38 MAPK (mitogen-activated protein kinase)/NOX4 (NADPH Oxidase 4) Axis-Associated Oxidative Stress. 2021 Aug 1
25 34197004 Exosomes from human umbilical cord mesenchymal stem cells inhibit ROS production and cell apoptosis in human articular chondrocytes via the miR-100-5p/NOX4 axis. 2021 Oct 2
26 34198827 Carnosic Acid Attenuates an Early Increase in ROS Levels during Adipocyte Differentiation by Suppressing Translation of Nox4 and Inducing Translation of Antioxidant Enzymes. 2021 Jun 5 3
27 34209278 NOX4 Signaling Mediates Cancer Development and Therapeutic Resistance through HER3 in Ovarian Cancer Cells. 2021 Jun 30 4
28 34257808 NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma. 2021 3
29 34440842 Naja atra Cardiotoxin 1 Induces the FasL/Fas Death Pathway in Human Leukemia Cells. 2021 Aug 12 2
30 34486189 The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro. 2021 Nov 1
31 34650437 Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway. 2021 4
32 34682914 Oxidative Stress Induced by Reactive Oxygen Species (ROS) and NADPH Oxidase 4 (NOX4) in the Pathogenesis of the Fibrotic Process in Systemic Sclerosis: A Promising Therapeutic Target. 2021 Oct 19 3
33 34944680 Pharmacological Inhibition of NOX4 Improves Mitochondrial Function and Survival in Human Beta-Cells. 2021 Dec 8 3
34 31490096 Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome. 2020 Jan 3
35 31668924 Transmembrane Nox4 topology revealed by topological determination by Ubiquitin Fusion Assay, a novel method to uncover membrane protein topology. 2020 Jan 8 1
36 31991927 Endothelial response boosted by platelet lysate: the involvement of calcium toolkit. 2020 Jan 26 4
37 32072237 Reductive stress in striated muscle cells. 2020 Sep 1
38 32119711 Angiotensin II promotes podocyte injury by activating Arf6-Erk1/2-Nox4 signaling pathway. 2020 1
39 32183375 Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease. 2020 Mar 14 3
40 32227122 Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS. 2020 Apr 17 2
41 32348995 Glomerular Transcriptome Profiles in Focal Glomerulosclerosis: New Genes and Pathways for Steroid Resistance. 2020 3
42 32414400 The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis. 2020 May 15 3
43 32587469 Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery. 2020 1
44 32616654 The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein. 2020 Aug 14 4
45 32686857 Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis. 2020 Sep 1
46 32727517 IFI6 depletion inhibits esophageal squamous cell carcinoma progression through reactive oxygen species accumulation via mitochondrial dysfunction and endoplasmic reticulum stress. 2020 Jul 29 1
47 32736702 Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells. 2020 Aug 27 4
48 32863203 Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction. 2020 Sep 1
49 32878795 Setanaxib as a Potent Hypoxia-specific Therapeutic Agent Against Liver Cancer. 2020 Sep 4
50 33010578 The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction. 2020 Oct 1