Protein Name | angiotensinogen |
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Organism | Mus musculus |
Gene ID | 11606 |
Gene Symbol | Agt |
UniProt | Q3UTR7 (Q3UTR7_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
860
Total Number of Articles : 1370 |
Description |
angiotensinogen |
Gene Summary |
Enables type 1 angiotensin receptor binding activity and type 2 angiotensin receptor binding activity. Involved in positive regulation of cytokine production. Acts upstream of or within several processes, including nervous system development; positive regulation of protein phosphorylation; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including axial skeleton; central nervous system; foregut mesenchyme; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |