Reactive Oxygen Species

tumor protein p53 ; Homo sapiens







511 Article(s)
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1 34628485 p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4. 2022 Mar 2
2 34785775 Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo. 2022 Jan 3
3 34821461 Low concentrations of 17β-estradiol exacerbate tamoxifen resistance in breast cancer treatment through membrane estrogen receptor-mediated signaling pathways. 2022 Mar 1
4 34823034 Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells. 2022 Mar 1
5 34992144 Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells. 2022 Apr 1 10
6 35085581 Piperlongumine induces ROS mediated apoptosis by transcriptional regulation of SMAD4/P21/P53 genes and synergizes with doxorubicin in osteosarcoma cells. 2022 Feb 25 1
7 35107378 p53 Ubiquitination Comediated by HUWE1 and TRAF6 Contributes to White Spot Syndrome Virus Infection in Crustacean. 2022 Mar 23 6
8 35266593 Hsp90 inhibition protects brain endothelial cells against LPS-induced injury. 2022 Mar 10 2
9 35395477 Ultrasound-triggered reactive oxygen species effector nanoamplifier for enhanced combination therapy of mutant p53 tumors. 2022 Jul 5
10 35398141 Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells. 2022 May 1
11 35513212 Oxidative stress-amplified nanomedicine for intensified ferroptosis-apoptosis combined tumor therapy. 2022 May 6 1
12 35541904 The sphingosine kinase inhibitor SKI-V suppresses cervical cancer cell growth. 2022 1
13 35601652 Association of p53 with Neurodegeneration in Parkinson's Disease. 2022 2
14 32864863 Curcumin induced apoptosis is mediated through oxidative stress in mutated p53 and wild type p53 colon adenocarcinoma cell lines. 2021 Jan 2
15 33128380 Anticancer potential of myricetin bulk and nano forms in vitro in lymphocytes from myeloma patients. 2021 Jan 1
16 33137455 p53-dependent glutamine usage determines susceptibility to oxidative stress in radioresistant head and neck cancer cells. 2021 Jan 7
17 33179088 Role of the SIRT1/p53 regulatory axis in oxidative stress‑mediated granulosa cell apoptosis. 2021 Jan 1
18 33181285 Antrodia camphorata extract (ACE)-induced apoptosis is associated with BMP4 expression and p53-dependent ROS generation in human colon cancer cells. 2021 Mar 25 6
19 33271245 Methoxyeugenol regulates the p53/p21 pathway and suppresses human endometrial cancer cell proliferation. 2021 Mar 1 1
20 33325610 Butein induces cellular senescence through reactive oxygen species-mediated p53 activation in osteosarcoma U-2 OS cells. 2021 May 2
21 33356180 Diclofenac Sodium Triggers p53-Dependent Apoptosis in Human Corneal Epithelial Cells via ROS-Mediated Crosstalk. 2021 Jan 18 1
22 33446200 Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells. 2021 Jan 14 1
23 33498875 Possible Beneficial Effects of N-Acetylcysteine for Treatment of Triple-Negative Breast Cancer. 2021 Jan 24 1
24 33542214 Loss-of-function of p53 isoform Δ113p53 accelerates brain aging in zebrafish. 2021 Feb 4 1
25 33546421 Targeting Redox Metabolism in Pancreatic Cancer. 2021 Feb 3 1
26 33670160 Regulation of p53 by E3s. 2021 Feb 11 2
27 33713969 The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway. 2021 May 1
28 33781788 T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells. 2021 Jun 2
29 33782397 Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair. 2021 Mar 29 1
30 33857626 Sodium fluoride activates the extrinsic apoptosis via regulating NOX4/ROS-mediated p53/DR5 signaling pathway in lung cells both in vitro and in vivo. 2021 Jun 2
31 33925065 Potential Antitumor Effects of 6-Gingerol in p53-Dependent Mitochondrial Apoptosis and Inhibition of Tumor Sphere Formation in Breast Cancer Cells. 2021 Apr 28 1
32 33992677 Transcriptional reprogramming by oxidative stress occurs within a predefined chromatin accessibility landscape. 2021 Aug 1 1
33 34131139 iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4. 2021 Jun 15 2
34 34144191 DNA damage and oxidant stress activate p53 through differential upstream signaling pathways. 2021 Aug 20 2
35 34181793 Surfactin induces autophagy, apoptosis, and cell cycle arrest in human oral squamous cell carcinoma. 2021 Jun 28 1
36 34239689 UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway. 2021 2
37 34405016 Dual Role of Reactive Oxygen Species and their Application in Cancer Therapy. 2021 1
38 34506766 A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells. 2021 Oct 1 2
39 34676202 Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells. 2021 1
40 34687773 Cylindrospermopsin impairs vascular smooth muscle cells by P53-mediated apoptosis due to ROS overproduction. 2021 Dec 15 1
41 34697746 The Effects of P53 in the Globular Heads of the C1q Receptor in Gastric Carcinoma Cell Apoptosis Are Exerted via a Mitochondrial-Dependent Pathway. 2021 Sep 1
42 34886886 Roles of reactive oxygen species, mitochondrial membrane potential, and p53 in evodiamine-induced apoptosis and G2/M arrest of human anaplastic thyroid carcinoma cells. 2021 Dec 9 2
43 34928029 An Efficient Carbon-Based Drug Delivery System for Cancer Therapy through the Nucleus Targeting and Mitochondria Mediated Apoptotic Pathway. 2021 Dec 2
44 31691131 M1 macrophage dependent-p53 regulates the intracellular survival of mycobacteria. 2020 Feb 1
45 31875760 Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway. 2020 Dec 1
46 31894323 ROS/p53/miR‑335‑5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG‑3 cells. 2020 Mar 1
47 31995555 Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. 2020 2
48 32076462 ZNF143 Suppresses Cell Apoptosis and Promotes Proliferation in Gastric Cancer via ROS/p53 Axis. 2020 1
49 32093585 Protective effects of 1,25 dihydroxyvitamin D3 and its analogs on ultraviolet radiation-induced oxidative stress: a review. 2020 Dec 1
50 32111081 Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells. 2020 Feb 26 5