Reactive Oxygen Species

mitogen-activated protein kinase 8 ; Homo sapiens







484 Article(s)
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1 34763314 The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway. 2022 Jan 4
2 34826531 Sequential delivery for hepatic fibrosis treatment based on carvedilol loaded star-like nanozyme. 2022 Jan 2
3 35044214 Hepatitis C Virus-Induced ROS/JNK Signaling Pathway Activates the E3 Ubiquitin Ligase Itch to Promote the Release of HCV Particles via Polyubiquitylation of VPS4A. 2022 Mar 23 5
4 35259676 Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway. 2022 May 3
5 35315184 Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells. 2022 Mar 21 1
6 35359571 The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells. 2022 2
7 35427423 Transient Inhibition of the JNK Pathway Promotes Human Hematopoietic Stem Cell Quiescence and Engraftment. 2022 Jun 22 2
8 35571453 Berberine induces non-small cell lung cancer apoptosis via the activation of the ROS/ASK1/JNK pathway. 2022 Apr 5
9 33039870 Bisphenol A induces apoptosis through GPER-dependent activation of the ROS/Ca2+-ASK1-JNK pathway in human granulosa cell line KGN. 2021 Jan 15 2
10 33045079 Activated Beta-Catenin Signaling Ameliorates Radiation-Induced Skin Injury by Suppressing Marvel D3 Expression. 2021 Feb 1 1
11 33159186 A transition to degeneration triggered by oxidative stress in degenerative disorders. 2021 Mar 1
12 33502699 Synergistic anticancer effect of docosahexaenoic acid and isoliquiritigenin on human colorectal cancer cells through ROS-mediated regulation of the JNK and cytochrome c release. 2021 Feb 3
13 33532038 Emodin Induced Necroptosis and Inhibited Glycolysis in the Renal Cancer Cells by Enhancing ROS. 2021 1
14 33589596 Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity. 2021 Feb 15 2
15 33613824 Coronary Endothelium No-Reflow Injury Is Associated with ROS-Modified Mitochondrial Fission through the JNK-Drp1 Signaling Pathway. 2021 3
16 33674562 Ciclopirox and bortezomib synergistically inhibits glioblastoma multiforme growth via simultaneously enhancing JNK/p38 MAPK and NF-κB signaling. 2021 Mar 5 4
17 33778293 Power of an Organic Electron Acceptor in Modulation of Intracellular Mitochondrial Reactive Oxygen Species: Inducing JNK- and Caspase-Dependent Apoptosis of Cancer Cells. 2021 Mar 23 2
18 33791802 Cytotoxicity mechanisms of plumbagin in drug-resistant tongue squamous cell carcinoma. 2021 Mar 1 1
19 33803748 Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo. 2021 Mar 18 2
20 33806765 Role of the ROS-JNK Signaling Pathway in Hypoxia-Induced Atrial Fibrotic Responses in HL-1 Cardiomyocytes. 2021 Mar 23 2
21 33871094 Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in LPS-induced neutrophil extracellular traps. 2021 Jul 3
22 33895649 The 3-deoxysappanchalcone induces ROS-mediated apoptosis and cell cycle arrest via JNK/p38 MAPKs signaling pathway in human esophageal cancer cells. 2021 Jun 2
23 33930940 Silver nanoparticles protect against arsenic induced genotoxicity via attenuating arsenic bioaccumulation and elevating antioxidation in mammalian cells. 2021 Jul 5 1
24 33959604 Isoalantolactone Increases the Sensitivity of Prostate Cancer Cells to Cisplatin Treatment by Inducing Oxidative Stress. 2021 2
25 34054302 Salusin-β Mediates High Glucose-Induced Inflammation and Apoptosis in Retinal Capillary Endothelial Cells via a ROS-Dependent Pathway in Diabetic Retinopathy. 2021 2
26 34107857 Neohesperidin Induces Cell Cycle Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells. 2021 1
27 34214663 The dependence of radio-sensitization efficiency on mitochondrial targeting with NaGdF4:Yb,Er nanoparticles. 2021 Sep 1 2
28 34242793 Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells. 2021 Aug 20 3
29 34280394 Role of 5-HT degradation in acute liver injury induced by carbon tetrachloride. 2021 Oct 5 1
30 34290233 Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism. 2021 Jul 21 2
31 34305590 Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells. 2021 1
32 34367464 Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency. 2021 1
33 34369083 Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. 2021 Sep 7 4
34 34413791 Abnormal Mitochondria-Endoplasmic Reticulum Communication Promotes Myocardial Infarction. 2021 1
35 34468764 Magnesium isoglycyrrhizinate prevents cadmium-induced activation of JNK and apoptotic hepatocyte death by reversing ROS-inactivated PP2A. 2021 Dec 7 2
36 34475984 Anti-proliferative, pro-apoptotic and anti-invasive effect of the copper coordination compound Cas III-La through the induction of reactive oxygen species and regulation of Wnt/β-catenin pathway in glioma. 2021 1
37 34481340 Rhopaloic acid A induces apoptosis, autophagy and MAPK activation through ROS-mediated signaling in bladder cancer. 2021 Nov 1
38 34494324 Luteolin combined with low-dose paclitaxel synergistically inhibits epithelial-mesenchymal transition and induces cell apoptosis on esophageal carcinoma in vitro and in vivo. 2021 Nov 2
39 34578957 Kaempferol Blocks the Skin Fibroblastic Interleukin 1β Expression and Cytotoxicity Induced by 12-O-tetradecanoylphorbol-13-acetate by Suppressing c-Jun N-terminal Kinase. 2021 Sep 1 4
40 34683920 Induction of Apoptosis by Isoalantolactone in Human Hepatocellular Carcinoma Hep3B Cells through Activation of the ROS-Dependent JNK Signaling Pathway. 2021 Oct 6 3
41 34776955 ROS/JNK/C-Jun Pathway is Involved in Chaetocin Induced Colorectal Cancer Cells Apoptosis and Macrophage Phagocytosis Enhancement. 2021 1
42 34834209 Regulation of ROS-Dependent JNK Pathway by 2'-Hydroxycinnamaldehyde Inducing Apoptosis in Human Promyelocytic HL-60 Leukemia Cells. 2021 Oct 26 2
43 31707583 Licochalcone H Synthesized by Modifying Structure of Licochalcone C Extracted from Glycyrrhiza inflata Induces Apoptosis of Esophageal Squamous Cell Carcinoma Cells. 2020 Mar 1
44 31756635 Acetaldehyde induces phosphorylation of dynamin-related protein 1 and mitochondrial dysfunction via elevating intracellular ROS and Ca2+ levels. 2020 Jan 6
45 32106366 Magnoflorine inhibits human gastric cancer progression by inducing autophagy, apoptosis and cell cycle arrest by JNK activation regulated by ROS. 2020 May 1
46 32131874 The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3. 2020 Mar 4 1
47 32236589 Andrographolide induces apoptosis in human osteosarcoma cells via the ROS/JNK pathway. 2020 Jun 3
48 32260423 Novel Anthraquinone Compounds Inhibit Colon Cancer Cell Proliferation via the Reactive Oxygen Species/JNK Pathway. 2020 Apr 4 2
49 32294550 Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma. 2020 Jun 1
50 32308415 Irinotecan Induces Autophagy-Dependent Apoptosis and Positively Regulates ROS-Related JNK- and P38-MAPK Pathways in Gastric Cancer Cells. 2020 2