| Protein Name | NADPH oxidase 4 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 50490 |
| Gene Symbol | Nox4 |
| UniProt | Q9JHI8 (NOX4_MOUSE), B2RSM1 (B2RSM1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
285
Total Number of Articles : 520 |
Description |
NADPH oxidase 4 |
| Gene Summary |
Enables protein tyrosine kinase binding activity and superoxide-generating NAD(P)H oxidase activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of intracellular signal transduction; and superoxide anion generation. Acts upstream of or within bone resorption and cardiac muscle cell differentiation. Located in cell periphery; mitochondrion; and perinuclear region of cytoplasm. Is expressed in embryo; heart; metanephros; renal cortex; and ventricle compact myocardium. Orthologous to human NOX4 (NADPH oxidase 4). [provided by Alliance of Genome Resources, Jul 2025] |
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