Reactive Oxygen Species

NADPH oxidase 4 ; Mus musculus







185 Article(s)
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1 34801525 SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species. 2022 Jan 2
2 34802139 Nox4-IGF2 Axis Promotes Differentiation of Embryoid Body Cells Into Derivatives of the Three Embryonic Germ Layers. 2022 Mar 2
3 35124000 Glucagon-like peptide-1 receptor activation by liraglutide promotes breast cancer through NOX4/ROS/VEGF pathway. 2022 Apr 1 1
4 35182975 Icariin inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells via inhibition of reactive oxygen species production by reducing the expression of NOX1 and NOX4. 2022 Apr 16 1
5 35275988 Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways. 2022 Jun 1 1
6 35354309 NADPH Oxidase 1 Mediates Acute Blood Pressure Response to Angiotensin II by Contributing to Calcium Influx in Vascular Smooth Muscle Cells. 2022 May 2
7 35408982 Hypomagnetic Field Induces the Production of Reactive Oxygen Species and Cognitive Deficits in Mice Hippocampus. 2022 Mar 26 1
8 35524333 AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model. 2022 May 6 5
9 32533834 Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1. 2021 Mar 21 1
10 33116250 β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of NOX4. 2021 Jul 2
11 33332718 Salvianolate ameliorates oxidative stress and podocyte injury through modulation of NOX4 activity in db/db mice. 2021 Jan 4
12 33367789 Targeted deletion of nicotinamide adenine dinucleotide phosphate oxidase 4 from proximal tubules is dispensable for diabetic kidney disease development. 2021 May 27 2
13 33400973 Nox4 mediates skeletal muscle metabolic responses to exercise. 2021 Mar 4
14 33486482 Schisandrin B Protects against Acute Ethanol-Induced Cardiac Injury by Downregulating Autophagy via the NOX4/ROS Pathway. 2021 2
15 33578912 Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient Mice. 2021 Feb 10 2
16 33789124 Nox4-dependent upregulation of S100A4 after peripheral nerve injury modulates neuropathic pain processing. 2021 May 20 4
17 33802941 NOX4 Mediates Pseudomonas aeruginosa-Induced Nuclear Reactive Oxygen Species Generation and Chromatin Remodeling in Lung Epithelium. 2021 Mar 17 3
18 33818129 Hepatic transcriptional profile reveals the role of diet and genetic backgrounds on metabolic traits in female progenitor strains of the Collaborative Cross. 2021 May 1 2
19 33823244 Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury. 2021 May 20 2
20 33824697 NOX4-Derived ROS Promotes Collagen I Deposition in Bronchial Smooth Muscle Cells by Activating Noncanonical p38MAPK/Akt-Mediated TGF-β Signaling. 2021 1
21 33836590 Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors. 2021 Mar 16 2
22 33875782 MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4. 2021 Apr 2
23 34023385 NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression. 2021 Jul 2
24 34523690 Ginsenoside Rg1 ameliorates aging‑induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice. 2021 Nov 1
25 34528872 Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial stem cells. 2021 Sep 16 3
26 34605573 Cardiomyocyte-specific miR-100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36. 2021 Nov 1
27 34740322 NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma. 2021 Nov 5 5
28 30937452 NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes post-ischaemic revascularization. 2020 Feb 1 5
29 31914694 Enhancer of zeste homolog 2 modulates oxidative stress-mediated pyroptosis in vitro and in a mouse kidney ischemia-reperfusion injury model. 2020 Jan 3
30 31926131 Nox4-mediated ROS production is involved, but not essential for TGFβ-induced lens EMT leading to cataract. 2020 Mar 5
31 32209423 Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia. 2020 Jun 1 1
32 32219126 Transient Receptor Potential Channel Canonical Type 3 Deficiency Antagonizes Myofibroblast Transdifferentiation In Vivo. 2020 2
33 32240965 Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease. 2020 Jun 2
34 32506037 Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle. 2020 Sep 2
35 32555397 Transient Receptor Potential Vanilloid channel regulates fibroblast differentiation and airway remodeling by modulating redox signals through NADPH Oxidase 4. 2020 Jun 17 3
36 32635630 The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney. 2020 Jul 5 1
37 32724174 Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway. 2020 Dec 4
38 32863203 Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction. 2020 Sep 1
39 32924342 Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress. 2020 Sep 14 4
40 32936698 Hypoxia-inducible factor-1 mediates pancreatic β-cell dysfunction by intermittent hypoxia. 2020 Nov 1 1
41 33010578 The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction. 2020 Oct 2
42 33052238 ROS production and mitochondrial dysfunction driven by PU.1-regulated NOX4-p22phox activation in Aβ-induced retinal pigment epithelial cell injury. 2020 1
43 33227845 Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression. 2020 Dec 1
44 30528855 Nox4 Promotes Neural Stem/Precursor Cell Proliferation and Neurogenesis in the Hippocampus and Restores Memory Function Following Trimethyltin-Induced Injury. 2019 Feb 1 1
45 30610956 Nox4 and soluble epoxide hydrolase synergistically mediate homocysteine-induced inflammation in vascular smooth muscle cells. 2019 Sep 4
46 30669315 Inhibition of NADPH Oxidase 4 (NOX4) Signaling Attenuates Tuberculous Pleural Fibrosis. 2019 Jan 18 4
47 30703252 Hypoxia improves hair inductivity of dermal papilla cells via nuclear NADPH oxidase 4-mediated reactive oxygen species generation'. 2019 Sep 1
48 30894481 From single drug targets to synergistic network pharmacology in ischemic stroke. 2019 Apr 2 2
49 31049140 NADPH Oxidase Isoforms Are Involved in Glucocorticoid-Induced Preosteoblast Apoptosis. 2019 2
50 31059059 Chronic stress augments esophageal inflammation, and alters the expression of transient receptor potential vanilloid 1 and protease‑activated receptor 2 in a murine model. 2019 Jun 1