Reactive Oxygen Species

Rac family small GTPase 1 ; Homo sapiens







161 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33852856 Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress. 2021 Apr 13 2
2 34064109 Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism. 2021 May 21 2
3 34597669 The eIF2 kinase GCN2 directs keratinocyte collective cell migration during wound healing via coordination of reactive oxygen species and amino acids. 2021 Nov 1
4 32133799 Inhibition of chemotherapy-related breast tumor EMT by application of redox-sensitive siRNA delivery system CSO-ss-SA/siRNA along with doxorubicin treatment. 2020 Mar 4
5 32178475 Rac1 Signaling: From Intestinal Homeostasis to Colorectal Cancer Metastasis. 2020 Mar 12 2
6 32300016 Resolvin E1 is a pro-repair molecule that promotes intestinal epithelial wound healing. 2020 Apr 28 2
7 32531347 Class I phosphoinositide 3-kinases control sustained NADPH oxidase activation in adherent neutrophils. 2020 Aug 1
8 32627008 Mitochondrial APE1 promotes cisplatin resistance by downregulating ROS in osteosarcoma. 2020 Aug 1
9 30105917 Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy. 2019 May 1 5
10 30279516 NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions. 2019 Jan 1
11 30396896 Bacterial Clearance Is Enhanced by α2,3- and α2,6-Sialyllactose via Receptor-Mediated Endocytosis and Phagocytosis. 2019 Jan 1
12 30553448 Loss of ATM positively regulates Rac1 activity and cellular migration through oxidative stress. 2019 Jan 22 4
13 30787155 HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity. 2019 May 1 6
14 31035701 Coordination between Rac1 and Rab Proteins: Functional Implications in Health and Disease. 2019 Apr 29 1
15 31172485 Using Synthetic Peptides for Exploring Protein-Protein Interactions in the Assembly of the NADPH Oxidase Complex. 2019 2
16 31216465 Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity. 2019 Jun 18 1
17 29186971 Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison. 2018 Dec 1 1
18 29330095 Crosstalk between Rac1-mediated actin regulation and ROS production. 2018 Feb 20 10
19 29462661 p66Shc regulates migration of castration-resistant prostate cancer cells. 2018 Jun 1
20 29740674 Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis. 2018 Jul 1
21 27380043 Tetramethylpyrazine Protects Against Oxygen-Glucose Deprivation-Induced Brain Microvascular Endothelial Cells Injury via Rho/Rho-kinase Signaling Pathway. 2017 May 1
22 27656113 Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. 2017 Jan 1 4
23 27779078 The Regulatory Roles of Mitogen-Activated Protein Kinase (MAPK) Pathways in Health and Diabetes: Lessons Learned from the Pancreatic β-Cell. 2017 2
24 28098862 Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in human ovarian carcinoma cells. 2017 Mar 2
25 29039574 TGF-β1-induced cell migration in pancreatic carcinoma cells is RAC1 and NOX4-dependent and requires RAC1 and NOX4-dependent activation of p38 MAPK. 2017 Dec 7
26 29163784 IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer. 2017 Oct 27 3
27 26795736 Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes. 2016 Aug 1
28 27048259 Actin depolymerization mediated loss of SNTA1 phosphorylation and Rac1 activity has implications on ROS production, cell migration and apoptosis. 2016 Jun 3
29 27681226 RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in Platelets. 2016 7
30 25677088 Rac1 modification by an electrophilic 15-deoxy Δ(12,14)-prostaglandin J2 analog. 2015 1
31 26079889 Omega-3 PUFA docosahexaenoic acid decreases LPS-stimulated MUC5AC production by altering EGFR-related signaling in NCI-H292 cells. 2015 Aug 7 1
32 26426686 IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype. 2015 Oct 1 1
33 26476350 Rap1 GTPase Inhibits Tumor Necrosis Factor-α-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-κB-Dependent Activation of Rac1. 2015 Dec 1
34 23919665 Rac1-mediated effects of HMG-CoA reductase inhibitors (statins) in cardiovascular disease. 2014 Mar 10 1
35 24434436 Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells. 2014 Feb 4 3
36 24554007 TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy. 2014 May 3
37 24583638 Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation. 2014 Jun 1
38 25249940 Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis. 2014 2
39 22358380 Expression of Ras-related C3 botulinum toxin substrate 1 (RAC1) in human cholesteatoma. 2013 Feb 1
40 22746102 A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis. 2013 Jan 1 3
41 23223568 A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation. 2013 Feb 4
42 23322165 NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activation. 2013 Apr 2
43 23375814 Pigment epithelium-derived factor (PEDF) inhibits survival and proliferation of VEGF-exposed multiple myeloma cells through its anti-oxidative properties. 2013 Feb 22 1
44 23461363 P66Shc-rac1 pathway-mediated ROS production and cell migration is downregulated by ascorbic acid. 2013 Apr 1
45 23465490 The antagonistic roles of PDGF and integrin αvβ3 in regulating ROS production at focal adhesions. 2013 May 1
46 23608189 Statins protect human endothelial cells from TNF-induced inflammation via ERK5 activation. 2013 Jun 15 1
47 23612479 8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. 2013 Aug 1
48 23637767 Annexin peptide Ac2-26 suppresses TNFα-induced inflammatory responses via inhibition of Rac1-dependent NADPH oxidase in human endothelial cells. 2013 1
49 23711511 Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2. 2013 Oct 1
50 23733346 A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress. 2013 Jun 10 2