Protein Name angiotensinogen
Organism Rattus norvegicus
Gene ID 24179
Gene Symbol

Agt

UniProt P01015 (ANGT_RAT)
Relationships Total Number of functionally related compound(s) : 2598
Total Number of Articles : 7729
Description

angiotensinogen

Gene Summary

Enables hormone activity. Involved in several processes, including MAPK cascade; regulation of ion transport; and regulation of secretion. Located in cytoplasm and extracellular space. Used to study several diseases, including artery disease (multiple); diabetic retinopathy; gastric ulcer; impotence; and sciatic neuropathy. Biomarker of several diseases, including cerebrovascular disease (multiple); glomerulonephritis (multiple); liver cirrhosis (multiple); lung disease (multiple); and prediabetes syndrome. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • angiotensinogen
  • angiotensin II
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
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Properties