Reactive Oxygen Species

amyloid beta precursor protein ; Homo sapiens







156 Article(s)
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1 35080532 Keggin-type polyoxometalates as Cu(II) chelators in the context of Alzheimer's disease. 2022 Feb 15 1
2 35101650 Synthesis, biological evaluation, and molecular modeling simulations of new heterocyclic hybrids as multi-targeted anti-Alzheimer's agents. 2022 Mar 5 2
3 33400522 Unexpected Trends in Copper Removal from Aβ Peptide: When Less Ligand Is Better and Zn Helps. 2021 Jan 18 2
4 33572224 Oxidative Stress Boosts the Uptake of Cerium Oxide Nanoparticles by Changing Brain Endothelium Microvilli Pattern. 2021 Feb 9 2
5 33724512 TTP488 ameliorates NLRP3-associated inflammation, viability, apoptosis, and ROS production in an Alzheimer's disease cell model by mediating the JAK1/STAT3/NFκB/IRF3 pathway. 2021 Jun 1
6 33761853 Piper sarmentosum Roxb. Attenuates Beta Amyloid (Aβ)-Induced Neurotoxicity Via the Inhibition of Amyloidogenesis and Tau Hyperphosphorylation in SH-SY5Y Cells. 2021 Mar 24 1
7 33807686 Diaportheone A Analogues Instigate a Neuroprotective Effect by Protecting Neuroblastoma SH-SY5Y Cells from Oxidative Stress. 2021 Mar 5 1
8 33839248 Design, synthesis and in-vitro evaluation of fluorinated triazoles as multi-target directed ligands for Alzheimer disease. 2021 Jun 15 1
9 33977683 Apelin-13 protects human neuroblastoma SH-SY5Y cells against amyloid-beta induced neurotoxicity: Involvement of anti oxidant and anti apoptotic properties. 2021 May 10 2
10 34048659 Disulfide-Rich Cyclic Peptides from Clitoria ternatea Protect against β-Amyloid Toxicity and Oxidative Stress in Transgenic Caenorhabditis elegans. 2021 Jun 10 3
11 34390299 Ordered Conformation-Regulated Vesicular Membrane Permeability. 2021 Oct 4 2
12 34450410 Inhibition of Aβ peptide aggregation by ruthenium(II) polypyridyl complexes through copper chelation. 2021 Nov 2
13 34510664 A Water-Soluble Peptoid Chelator that Can Remove Cu2+ from Amyloid-β Peptides and Stop the Formation of Reactive Oxygen Species Associated with Alzheimer's Disease. 2021 Nov 8 4
14 34586144 A diselenide bond-containing ROS-responsive ruthenium nanoplatform delivers nerve growth factor for Alzheimer's disease management by repairing and promoting neuron regeneration. 2021 Sep 29 1
15 34687443 SIRT3 Regulates Neuronal Excitability of Alzheimer's Disease Models in an Oxidative Stress-Dependent Manner. 2021 Oct 23 3
16 34988394 Amyloid-beta-copper interaction studied by simultaneous nitrogen K and copper L2,3 -edge soft X-ray absorption spectroscopy. 2021 Dec 17 1
17 32127013 Sinomenine inhibits amyloid beta-induced astrocyte activation and protects neurons against indirect toxicity. 2020 Mar 4 2
18 32272441 Antioxidant Berberine-Derivative Inhibits Multifaceted Amyloid Toxicity. 2020 Apr 24 2
19 32538407 Efficient suppression of amyloid-β peptide aggregation and cytotoxicity with photosensitive polymer nanodots. 2020 Jul 14 2
20 33052996 On the propagation of the OH radical produced by Cu-amyloid beta peptide model complexes. Insight from molecular modelling. 2020 Nov 1 4
21 33074279 Inhibition and disaggregation of amyloid β protein fibrils through conjugated polymer-core thermoresponsive micelles. 2020 Nov 18 5
22 30262061 Design and synthesis of thymine modified phthalocyanine for Aβ protofibrils photodegradation and Aβ peptide aggregation inhibition. 2019 Jan 1 2
23 30350305 Dopamine promotes cathepsin B-mediated amyloid precursor protein degradation by reactive oxygen species-sensitive mechanism in neuronal cell. 2019 Apr 1
24 30629288 Brusatol inhibits amyloid-β-induced neurotoxicity in U-251 cells via regulating the Nrf2/HO-1 pathway. 2019 Jun 1
25 30650306 d-Enantiomeric RTHLVFFARK-NH2: A Potent Multifunctional Decapeptide Inhibiting Cu2+-Mediated Amyloid β-Protein Aggregation and Remodeling Cu2+-Mediated Amyloid β Aggregates. 2019 Mar 20 2
26 30707915 Novel compound VB-037 inhibits Aβ aggregation and promotes neurite outgrowth through enhancement of HSP27 and reduction of P38 and JNK-mediated inflammation in cell models for Alzheimer's disease. 2019 May 4
27 30814823 Altered Micro-RNA Regulation and Neuroprotection Activity of Eremostachys labiosiformis in Alzheimer's Disease Model. 2019 Jan 1
28 31005822 Metal-dependent interactions of metallothionein-3 β-domain with amyloid-β peptide and related physiological implications. 2019 Jul 1
29 31079281 AGE-RAGE stress: a changing landscape in pathology and treatment of Alzheimer's disease. 2019 Sep 1
30 31191308 Pharmacological Potential of Cilostazol for Alzheimer's Disease. 2019 1
31 31247877 Copper-Targeting Approaches in Alzheimer's Disease: How To Improve the Fallouts Obtained from in Vitro Studies. 2019 Oct 21 3
32 31254862 A label-free and signal-on electrochemiluminescence strategy for sensitive amyloid-beta assay. 2019 Sep 15 4
33 31344860 Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells. 2019 Jul 24 2
34 31371134 Inhibition of β-amyloid-induced neurotoxicity by planar analogues of procyanidin B3. 2019 Sep 15 5
35 31419776 Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease. 2019 Nov 15 2
36 31722188 Amentoflavone suppresses amyloid β1-42 neurotoxicity in Alzheimer's disease through the inhibition of pyroptosis. 2019 Dec 15 4
37 29080524 Oxidative stress and the amyloid beta peptide in Alzheimer's disease. 2018 Apr 2
38 29107864 TRPM2 dependence of ROS-induced NLRP3 activation in Alzheimer's disease. 2018 Jan 3
39 29330223 The antioxidant xanthorrhizol prevents amyloid-β-induced oxidative modification and inactivation of neprilysin. 2018 Feb 28 4
40 29330470 β-Ecdysterone protects SH-SY5Y cells against β-amyloid-induced apoptosis via c-Jun N-terminal kinase- and Akt-associated complementary pathways. 2018 Apr 2
41 29611698 Ascorbate Oxidation by Cu(Amyloid-β) Complexes: Determination of the Intrinsic Rate as a Function of Alterations in the Peptide Sequence Revealing Key Residues for Reactive Oxygen Species Production. 2018 May 1 3
42 29782798 Regulatory Activities of Dopamine and Its Derivatives toward Metal-Free and Metal-Induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer's Disease. 2018 Nov 21 2
43 29920995 Redox-Activated Near-Infrared-Responsive Polyoxometalates Used for Photothermal Treatment of Alzheimer's Disease. 2018 Oct 2
44 30031108 Neuroprotective effects of cordycepin inhibit Aβ-induced apoptosis in hippocampal neurons. 2018 Sep 2
45 30459926 Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system. 2018 1
46 27431297 Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. 2017 Apr 2
47 27662292 Aberrant Co-localization of Synaptic Proteins Promoted by Alzheimer's Disease Amyloid-β Peptides: Protective Effect of Human Serum Albumin. 2017 1
48 28059794 Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease. 2017 1
49 28241840 Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport. 2017 Feb 28 1
50 28242320 A positive feedback loop between nitric oxide and amyloid β (1-42) accelerates mitochondrial damage in human lens epithelial cells. 2017 Apr 15 1