Reactive Oxygen Species

epidermal growth factor receptor ; Homo sapiens







129 Article(s)
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1 35218706 Selective phosphorylation of serine 345 on p47-phox serves as a priming signal of ROS-mediated axonal degeneration. 2022 Jun 2
2 35381015 Role of urinary H2O2, 8-iso-PGF2α, and serum oxLDL/β2GP1 complex in the diabetic kidney disease. 2022 1
3 35568782 EGFR inhibition reverses resistance to lenvatinib in hepatocellular carcinoma cells. 2022 May 14 3
4 33994369 Cisplatin Activates the Growth Inhibitory Signaling Pathways by Enhancing the Production of Reactive Oxygen Species in Non-small Cell Lung Cancer Carrying an EGFR Exon 19 Deletion. 2021 May-Jun 1
5 34157521 Epidermal growth factor receptor and integrins meet redox signaling through P66shc and Rac1. 2021 Oct 2
6 34520834 Co-delivery of gefitinib and hematoporphyrin by aptamer-modified fluorinated dendrimer for hypoxia alleviation and enhanced synergistic chemo-photodynamic therapy of NSCLC. 2021 Dec 1 1
7 35126111 FGFC1 Selectively Inhibits Erlotinib-Resistant Non-Small Cell Lung Cancer via Elevation of ROS Mediated by the EGFR/PI3K/Akt/mTOR Pathway. 2021 1
8 31852834 EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma. 2020 Mar 15 2
9 31964804 Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation. 2020 Jan 21 4
10 32443749 Epidermal Growth Factor (EGF) Augments the Invasive Potential of Human Glioblastoma Multiforme Cells via the Activation of Collaborative EGFR/ROS-Dependent Signaling. 2020 May 20 1
11 33304472 EGFR-rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway-suppressed ROS. 2020 Oct 7
12 30273693 PAC1 regulates receptor tyrosine kinase transactivation in a reactive oxygen species-dependent manner. 2019 Oct 1
13 30365122 Vorinostat enhances gefitinib‑induced cell death through reactive oxygen species‑dependent cleavage of HSP90 and its clients in non‑small cell lung cancer with the EGFR mutation. 2019 Jan 1
14 30431083 EGFR mutation decreases FDG uptake in non‑small cell lung cancer via the NOX4/ROS/GLUT1 axis. 2019 Jan 1
15 30733286 AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. 2019 Feb 26 2
16 31216465 Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity. 2019 Jun 18 1
17 31360122 p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling. 2019 1
18 31454652 High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells. 2019 Nov 1
19 31491956 Lycopene Inhibits Activation of Epidermal Growth Factor Receptor and Expression of Cyclooxygenase-2 in Gastric Cancer Cells. 2019 Sep 5 4
20 32923966 GPCR transactivation signalling in vascular smooth muscle cells: role of NADPH oxidases and reactive oxygen species. 2019 1
21 29548337 The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance. 2018 Mar 16 6
22 29589623 Nanoparticle-cell interactions induced apoptosis: a case study with nanoconjugated epidermal growth factor. 2018 Apr 5 2
23 29659325 Reactive oxygen species mediates 50-Hz magnetic field-induced EGF receptor clustering via acid sphingomyelinase activation. 2018 Jul 3
24 29886055 Syringic acid prevents skin carcinogenesis via regulation of NoX and EGFR signaling. 2018 Aug 1
25 29945964 Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR Degradation. 2018 Aug 15 1
26 29977314 ROS-Mediated Mitochondrial Pathway is Required for Manilkara Zapota (L.) P. Royen Leaf Methanol Extract Inducing Apoptosis in the Modulation of Caspase Activation and EGFR/NF-κB Activities of HeLa Human Cervical Cancer Cells. 2018 1
27 30029165 Matrix metalloproteinase-2-induced epidermal growth factor receptor transactivation impairs redox balance in vascular smooth muscle cells and facilitates vascular contraction. 2018 Sep 1
28 30145116 Interdependence between EGFR and Phosphatases Spatially Established by Vesicular Dynamics Generates a Growth Factor Sensing and Responding Network. 2018 Sep 26 2
29 27942670 Fast quantitative ROS detection based on dual-color single rare-earth nanoparticle imaging reveals signaling pathway kinetics in living cells. 2017 Jan 5 2
30 28081539 Regulation of anoikis resistance by NADPH oxidase 4 and epidermal growth factor receptor. 2017 Jan 2
31 28137309 Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation. 2017 Jan 30 1
32 28222166 Correction: Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway. 2017 1
33 28236592 Novel conjugates of endoperoxide and 4-anilinoquinazoline as potential anticancer agents. 2017 Mar 15 1
34 28338196 Study on the proliferation of human gastric cancer cell AGS by activation of EGFR in H2O2. 2017 Mar 4
35 28394354 Oncogenic MCT-1 activation promotes YY1-EGFR-MnSOD signaling and tumor progression. 2017 Apr 10 1
36 28577939 Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines. 2017 Jul 2
37 29077771 Correction: Correction: Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway. 2017 1
38 29110853 CD44 variant-dependent regulation of redox balance in EGFR mutation-positive non-small cell lung cancer: A target for treatment. 2017 Nov 6
39 29123322 Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells. 2017 Nov 9 1
40 26286833 Src and epidermal growth factor receptor mediate the pro-invasive activity of Bcl-w. 2016 Jan 1
41 26528827 Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation. 2016 Feb 10 5
42 26747779 Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells. 2016 Apr 1 1
43 26815118 Caveolin-1-dependent activation of the metalloprotease TACE/ADAM17 by TGF-β in hepatocytes requires activation of Src and the NADPH oxidase NOX1. 2016 Apr 1
44 26904167 TGF-β and Hypoxia/Reoxygenation Promote Radioresistance of A549 Lung Cancer Cells through Activation of Nrf2 and EGFR. 2016 1
45 27195063 NADPH oxidases promote apoptosis by activating ZNRF1 ubiquitin ligase in neurons treated with an exogenously applied oxidant. 2016 Mar-Apr 1
46 27450723 ASCT2 (SLC1A5) is an EGFR-associated protein that can be co-targeted by cetuximab to sensitize cancer cells to ROS-induced apoptosis. 2016 Oct 10 1
47 27594973 Genome-Wide Transcriptional Analysis Reveals the Protection against Hypoxia-Induced Oxidative Injury in the Intestine of Tibetans via the Inhibition of GRB2/EGFR/PTPN11 Pathways. 2016 1
48 27650496 The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling. 2016 Oct 28 3
49 27744404 Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch. 2016 Oct 15 1
50 27846303 Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway. 2016 2