Reactive Oxygen Species

mitogen-activated protein kinase 3 ; Homo sapiens







267 Article(s)
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1 35294968 Oxidative Stress-induced Autophagy Compromises Stem Cell Viability. 2022 May 27 1
2 35453328 Ginsenoside Rh1 Inhibits Angiotensin II-Induced Vascular Smooth Muscle Cell Migration and Proliferation through Suppression of the ROS-Mediated ERK1/2/p90RSK/KLF4 Signaling Pathway. 2022 Mar 27 2
3 35464760 Thyroid Cancer-Associated Mitochondrial DNA Mutation G3842A Promotes Tumorigenicity via ROS-Mediated ERK1/2 Activation. 2022 3
4 35563563 Sulforaphane Suppresses the Nicotine-Induced Expression of the Matrix Metalloproteinase-9 via Inhibiting ROS-Mediated AP-1 and NF-κB Signaling in Human Gastric Cancer Cells. 2022 May 5 2
5 33109619 Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress. 2021 Jan 1
6 33471797 Perfluorooctane sulfonate induces autophagy-associated apoptosis through oxidative stress and the activation of extracellular signal-regulated kinases in renal tubular cells. 2021 1
7 33522955 FOXC1 promotes HCC proliferation and metastasis by Upregulating DNMT3B to induce DNA Hypermethylation of CTH promoter. 2021 Feb 1 2
8 33819767 Ginsenoside-Rg2 affects cell growth via regulating ROS-mediated AMPK activation and cell cycle in MCF-7 cells. 2021 May 1
9 33828192 Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure. 2021 Apr 7 1
10 34248106 Effects of omega-7 palmitoleic acids on skeletal muscle differentiation in a hyperglycemic condition. 2021 Sep 3 2
11 34439417 Study of the Antioxidant Effects of Coffee Phenolic Metabolites on C6 Glioma Cells Exposed to Diesel Exhaust Particles. 2021 Jul 23 1
12 34487308 Oxidative Stress Enhances Autophagy-Mediated Death Of Stem Cells Through Erk1/2 Signaling Pathway - Implications For Neurotransplantations. 2021 Dec 1
13 34634453 Mechanism of neutrophil extracellular traps generation and their role in trophoblasts apoptosis in gestational diabetes mellitus. 2021 Dec 1
14 34749347 DOX-loaded silver nanotriangles and photothermal therapy exert a synergistic antibreast cancer effect via ROS/ERK1/2 signaling pathway. 2021 Nov 22 2
15 34768994 Helicobacter pylori Neutrophil-Activating Protein Directly Interacts with and Activates Toll-like Receptor 2 to Induce the Secretion of Interleukin-8 from Neutrophils and ATRA-Induced Differentiated HL-60 Cells. 2021 Oct 26 1
16 32119711 Angiotensin II promotes podocyte injury by activating Arf6-Erk1/2-Nox4 signaling pathway. 2020 1
17 32251677 Apocynin prevents GM-CSF-induced-ERK1/2 activation and -neutrophil survival independently of its inhibitory effect on the phagocyte NADPH oxidase NOX2. 2020 Jul 4
18 32411325 Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. 2020 2
19 32431605 Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma. 2020 1
20 32521698 Chrysosplenol d, a Flavonol from Artemisia annua, Induces ERK1/2-Mediated Apoptosis in Triple Negative Human Breast Cancer Cells. 2020 Jun 8 2
21 32813234 Quercetin Ameliorates CFA-Induced Chronic Inflammatory Hyperalgesia via Modulation of ROS-Mediated ERK1/2 Signaling and Inhibition of Spinal Glial Activation In Vivo. 2020 Dec 2
22 33553145 Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells. 2020 1
23 30359932 A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells. 2019 Jan 1
24 30464227 Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis. 2019 Sep 3
25 30628067 Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3. 2019 Jul 1
26 30661992 Disrupting the vicious cycle created by NOX activation in sickle erythrocytes exposed to hypoxia/reoxygenation prevents adhesion and vasoocclusion. 2019 Jul 3
27 30701573 Anti-β2GPI/β2GPI induces human neutrophils to generate NETs by relying on ROS. 2019 Mar 1
28 30735839 Critical role of H2O2 in mediating sanguinarine-induced apoptosis in prostate cancer cells via facilitating ceramide generation, ERK1/2 phosphorylation, and Par-4 cleavage. 2019 Apr 1
29 30776374 Cardiac-specific deletion of GCN5L1 restricts recovery from ischemia-reperfusion injury. 2019 Apr 1
30 30811039 RAS/MAPK signaling functions in oxidative stress, DNA damage response and cancer progression. 2019 Feb 27 2
31 30844388 Unique mechanistic insights into the beneficial effects of angiotensin-(1-7) on the prevention of cardiac fibrosis: A metabolomic analysis of primary cardiac fibroblasts. 2019 May 15 1
32 31024318 Copper Chaperone for Superoxide Dismutase Promotes Breast Cancer Cell Proliferation and Migration via ROS-Mediated MAPK/ERK Signaling. 2019 2
33 31026097 α-Mangostin promotes apoptosis of human rheumatoid arthritis fibroblast-like synoviocytes by reactive oxygen species-dependent activation of ERK1/2 mitogen-activated protein kinase. 2019 Sep 1
34 31123601 Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production. 2019 1
35 31129114 ML171, a specific inhibitor of NOX1 attenuates formalin induced nociceptive sensitization by inhibition of ROS mediated ERK1/2 signaling. 2019 Oct 2
36 31238089 Deferoxamine inhibits iron-uptake stimulated osteoclast differentiation by suppressing electron transport chain and MAPKs signaling. 2019 Oct 1 1
37 31254584 The novel diterpene 7β-acetoxy-20-hydroxy-19,20-epoxyroyleanone from Salvia corrugata shows complex cytotoxic activities against human breast epithelial cells. 2019 Sep 1 2
38 31261663 Carbon Monoxide Releasing Molecule-2-Upregulated ROS-Dependent Heme Oxygenase-1 Axis Suppresses Lipopolysaccharide-Induced Airway Inflammation. 2019 Jun 28 1
39 28876465 Procyanidin B2 3,3″-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK. 2018 Jan 1
40 29084209 MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells. 2018 Feb 22 1
41 29140787 TGF-β requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy. 2018 Feb 23 1
42 29423117 Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation. 2018 Jan 9 1
43 29549478 Metformin Promotes HaCaT Cell Apoptosis through Generation of Reactive Oxygen Species via Raf-1-ERK1/2-Nrf2 Inactivation. 2018 Jun 1
44 29568362 The metal-nonoate Ni(SalPipNONO) inhibits in vitro tumor growth, invasiveness and angiogenesis. 2018 Mar 2 2
45 29627441 Amentoflavone-induced oxidative stress activates NF-E2-related factor 2 via the p38 MAP kinase-AKT pathway in human keratinocytes. 2018 Jun 1
46 29672044 Andrographolide Antagonizes TNF-α-Induced IL-8 via Inhibition of NADPH Oxidase/ROS/NF-κB and Src/MAPKs/AP-1 Axis in Human Colorectal Cancer HCT116 Cells. 2018 May 23 1
47 29768263 Fibrinopeptide A Induces Expression of C-Reactive Protein via the ROS-ERK1/2/ P38-NF-κB Signal Pathway in Vascular Smooth Muscle Cells. 2018 2
48 29906487 Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction. 2018 Sep 28 2
49 30006481 Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease. 2018 Jul 31 2
50 30011321 A 60 Hz uniform electromagnetic field promotes human cell proliferation by decreasing intracellular reactive oxygen species levels. 2018 1