Protein Name superoxide dismutase 2
Organism Homo sapiens
Gene ID 6648
Gene Symbol


UniProt P04179 (SODM_HUMAN), G5E9P6 (G5E9P6_HUMAN), A0A384NL29 (A0A384NL29_HUMAN), Q9UG59 (Q9UG59_HUMAN), Q96AM7 (Q96AM7_HUMAN)
Relationships Total Number of functionally related compound(s) : 841
Total Number of Articles : 1683

superoxide dismutase 2

Gene Summary

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]

  • superoxide dismutase [Mn], mitochondrial
  • Mn superoxide dismutase
  • epididymis secretory sperm binding protein
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