Reactive Oxygen Species

transforming growth factor beta 1 ; Homo sapiens







240 Article(s)
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1 34468828 Lobeglitazone attenuates fibrosis in corneal fibroblasts by interrupting TGF-beta-mediated Smad signaling. 2022 Jan 3
2 34993544 Generation of endoplasmic reticulum stress-dependent reactive oxygen species mediates TGF-β1-induced podocyte migration. 2022 Mar 3 4
3 35092472 Astragaloside IV suppresses migration and invasion of TGF-β1-induced human hepatoma HuH-7 cells by regulating Nrf2/HO-1 and TGF-β1/Smad3 pathways. 2022 Apr 1
4 35100464 HPV+ HNSCC-derived exosomal miR-9-5p inhibits TGF-β signaling-mediated fibroblast phenotypic transformation through NOX4. 2022 Apr 4
5 35184673 Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment. 2022 Mar 1
6 35330181 Microvasculopathy-Related Hemorrhagic Tissue Deposition of Iron May Contribute to Fibrosis in Systemic Sclerosis: Hypothesis-Generating Insights from the Literature and Preliminary Findings. 2022 Mar 16 1
7 33325804 Profibrotic epithelial TGF-β1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN. 2021 Mar 1 1
8 33351681 Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms. 2021 Feb 1
9 33440354 Aqueous two-phase deposition and fibrinolysis of fibroblast-laden fibrin micro-scaffolds. 2021 Apr 7 2
10 33448057 Antioxidants protect against gingival overgrowth induced by cyclosporine A. 2021 Apr 1
11 33559185 Blockade of mTORC1-NOX signaling pathway inhibits TGF-β1-mediated senescence-like structural alterations of the retinal pigment epithelium. 2021 Mar 2
12 33806765 Role of the ROS-JNK Signaling Pathway in Hypoxia-Induced Atrial Fibrotic Responses in HL-1 Cardiomyocytes. 2021 Mar 23 1
13 33925714 Effects of High Glucose Concentration on Pericyte-Like Differentiated Human Adipose-Derived Mesenchymal Stem Cells. 2021 Apr 27 2
14 34257808 NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma. 2021 4
15 34568577 Scutellarin-induced A549 cell apoptosis depends on activation of the transforming growth factor-β1/smad2/ROS/caspase-3 pathway. 2021 1
16 34763128 ROS-Nrf2 pathway mediates the development of TGF-β1-induced epithelial-mesenchymal transition through the activation of Notch signaling. 2021 Sep-Nov 5
17 32197075 Bi-allelic LoF NRROS Variants Impairing Active TGF-β1 Delivery Cause a Severe Infantile-Onset Neurodegenerative Condition with Intracranial Calcification. 2020 Apr 2 3
18 32273698 Involvement of TGF-β and ROS in G1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Under UVA Irradiation in a 3D Spheroid Model. 2020 2
19 32281291 RUNX1 and TGF-β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development. 2020 Dec 2
20 32319705 The TGF-b/SOX4 axis and ROS-driven autophagy co-mediate CD39 expression in regulatory T-cells. 2020 Jun 2
21 32471991 TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cells. 2020 May 29 3
22 32512009 Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-β1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis - A review. 2020 Sep 1 2
23 32514269 Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal mesothelial cell line HMrSV5. 2020 2
24 32555397 Transient Receptor Potential Vanilloid channel regulates fibroblast differentiation and airway remodeling by modulating redox signals through NADPH Oxidase 4. 2020 Jun 17 2
25 32580467 TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress. 2020 Jun 22 2
26 32697292 Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repression. 2020 Sep 18 1
27 32736702 Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells. 2020 Aug 27 4
28 32980322 TGF-β1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. 2020 Nov 1 2
29 33242180 NRF2 level is negatively correlated with TGF-β1-induced lung cancer motility and migration via NOX4-ROS signaling. 2020 Dec 7
30 33376719 10-HDA Induces ROS-Mediated Apoptosis in A549 Human Lung Cancer Cells by Regulating the MAPK, STAT3, NF-κB, and TGF-β1 Signaling Pathways. 2020 2
31 33585469 Mitochondrial Fission and Mitophagy Reciprocally Orchestrate Cardiac Fibroblasts Activation. 2020 3
32 30317545 Arsenic trioxide inhibits the differentiation of fibroblasts to myofibroblasts through nuclear factor erythroid 2-like 2 (NFE2L2) protein and the Smad2/3 pathway. 2019 Mar 1
33 30354670 Paricalcitol attenuates TGF-β1-induced phenotype transition of human peritoneal mesothelial cells (HPMCs) via modulation of oxidative stress and NLRP3 inflammasome. 2019 Feb 1
34 30365941 Delphinidin protects β2m-/Thy1+ bone marrow-derived hepatocyte stem cells against TGF-β1-induced oxidative stress and apoptosis through the PI3K/Akt pathway in vitro. 2019 Jan 5 1
35 30417274 Transforming growth factor-β1 mediated CHST11 and CHSY1 mRNA expression is ROS dependent in vascular smooth muscle cells. 2019 Jun 4
36 30465855 Vitamin D inhibits the epithelial-mesenchymal transition by a negative feedback regulation of TGF-β activity. 2019 Mar 1
37 30975276 [TGF-β1 activates NOX4/ROS pathway to promote the invasion and migration of cervical cancer cells]. 2019 Feb 5
38 30982574 Fucoxanthin exerts anti-fibrogenic effects in hepatic stellate cells. 2019 Jun 4 1
39 31119153 Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation. 2019 1
40 31127990 Effect of TGF-β1 on Apoptosis of Colon Cancer Cells Via the ERK Signaling Pathway. 2019 Mar-Apr 2
41 31140862 Lipid Peroxidation and GPX4 Inhibition Are Common Causes for Myofibroblast Differentiation and Ferroptosis. 2019 Jul 2
42 31147528 TGF-β mediates aortic smooth muscle cell senescence in Marfan syndrome. 2019 May 30 2
43 31387985 Hydrogen peroxide inducible clone-5 sustains NADPH oxidase-dependent reactive oxygen species-c-jun N-terminal kinase signaling in hepatocellular carcinoma. 2019 Aug 6 2
44 31432132 TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production. 2019 Oct 3
45 28815354 NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway. 2018 Feb 5
46 29140787 TGF-β requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy. 2018 Feb 23 3
47 29230000 Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma. 2018 May 1
48 29294389 NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy. 2018 Feb 20 2
49 29385685 MiR200 and miR302: Two Big Families Influencing Stem Cell Behavior. 2018 Jan 30 1
50 29408318 Cadmium disrupts signaling of the hypoxia-inducible (HIF) and transforming growth factor (TGF-β) pathways in placental JEG-3 trophoblast cells via reactive oxygen species. 2018 Mar 1 1