Reactive Oxygen Species

synuclein alpha ; Homo sapiens







159 Article(s)
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1 33894036 Astragaloside prevents UV-induced keratinocyte injury by regulating TLR4/NF-κB pathway. 2022 Mar 2
2 34625658 Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O6-methylguanine DNA methyltransferase (MGMT) expression and reactive oxygen species (ROS)-mediated DNA damage in glioblastoma. 2022 Feb 1
3 34838943 Antioxidative role of Traditional Chinese Medicine in Parkinson's disease. 2022 Mar 1 6
4 35054862 Mechanistic Insights Expatiating the Redox-Active-Metal-Mediated Neuronal Degeneration in Parkinson's Disease. 2022 Jan 8 2
5 35128947 Taraxasterol attenuates melanoma progression via inactivation of reactive oxygen species-mediated PI3K/Akt signaling pathway. 2022 Jan-Dec 4
6 35215851 Levistolide A Inhibits PEDV Replication via Inducing ROS Generation. 2022 Jan 27 2
7 35413176 Understanding the Inhibitory and Antioxidant Effects of Pyrroloquinoline Quinone (PQQ) on Copper(II)-Induced α-Synuclein-119 Aggregation. 2022 Apr 20 2
8 35483142 The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin. 2022 Jun 1 2
9 32814819 A novel Diels-Alder adduct of mulberry leaves exerts anticancer effect through autophagy-mediated cell death. 2021 May 3
10 33039870 Bisphenol A induces apoptosis through GPER-dependent activation of the ROS/Ca2+-ASK1-JNK pathway in human granulosa cell line KGN. 2021 Jan 15 1
11 33181285 Antrodia camphorata extract (ACE)-induced apoptosis is associated with BMP4 expression and p53-dependent ROS generation in human colon cancer cells. 2021 Mar 25 2
12 33494411 Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson's Disease Targeting Neuroinflammation. 2021 Jan 21 2
13 33589596 Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity. 2021 Feb 15 2
14 33826406 Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism. 2021 Jun 1 3
15 33912013 Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation. 2021 1
16 34216695 GAPDH siRNA Regulates SH-SY5Y Cell Apoptosis Induced by Exogenous α-Synuclein Protein. 2021 Aug 10 1
17 34547383 Doxorubicin suppresses chondrocyte differentiation by stimulating ROS production. 2021 Dec 1 2
18 34680141 Mitochondrial Dysfunction, Protein Misfolding and Neuroinflammation in Parkinson's Disease: Roads to Biomarker Discovery. 2021 Oct 13 3
19 32106377 Ginkgolic acid (GA) suppresses gastric cancer growth by inducing apoptosis and suppressing STAT3/JAK2 signaling regulated by ROS. 2020 May 1
20 32124960 Icariin sensitizes human colon cancer cells to TRAIL‑induced apoptosis via ERK‑mediated upregulation of death receptors. 2020 Mar 1
21 32154238 Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation. 2020 1
22 32160287 Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease. 2020 May 8 1
23 32226300 Bisdemethoxycurcumin Enhances the Sensitivity of Non-small Cell Lung Cancer Cells to Icotinib via Dual Induction of Autophagy and Apoptosis. 2020 1
24 32245324 In Vitro Effects of Curcumin on Transforming Growth Factor-β-mediated Non-Smad Signaling Pathway, Oxidative Stress, and Pro-inflammatory Cytokines Production with Human Vascular Smooth Muscle Cells. 2020 Feb 1 1
25 32409937 Reducing state attenuates ectodomain shedding of GPVI while restoring adhesion capacities of stored platelets: evidence addressing the controversy around the effects of redox condition on thrombosis. 2020 Jul 1
26 32446561 Antioxidants suppress radiation-induced apoptosis via inhibiting MAPK pathway in nasopharyngeal carcinoma cells. 2020 Jun 30 1
27 32477104 A Novel Benzofuran Derivative Moracin N Induces Autophagy and Apoptosis Through ROS Generation in Lung Cancer. 2020 3
28 32479946 Novel eIF4E/eIF4G protein-protein interaction inhibitors DDH-1 exhibits anti-cancer activity in vivo and in vitro. 2020 Oct 1 1
29 32773102 Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression. 2020 Aug 1
30 32945484 Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC‑27. 2020 Oct 1
31 33211011 Megadalton-sized Dityrosine Aggregates of α-Synuclein Retain High Degrees of Structural Disorder and Internal Dynamics. 2020 Dec 4 1
32 30273693 PAC1 regulates receptor tyrosine kinase transactivation in a reactive oxygen species-dependent manner. 2019 Oct 1
33 30552901 2-Bromopalmitate sensitizes osteosarcoma cells to adriamycin-induced apoptosis via the modulation of CHOP. 2019 Feb 5 2
34 30769285 Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth. 2019 Apr 1
35 30804337 Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells. 2019 Feb 25 1
36 30896843 α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation. 2019 May 2
37 30911317 Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells. 2019 3
38 30973706 Nitration and Glycation Diminish the α-Synuclein Role in the Formation and Scavenging of Cu2+-Catalyzed Reactive Oxygen Species. 2019 Jun 19 1
39 30992317 Starvation-induced autophagy is up-regulated via ROS-mediated ClC-3 chloride channel activation in the nasopharyngeal carcinoma cell line CNE-2Z. 2019 May 7 2
40 31019655 Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway. 2019 1
41 31090954 MicroRNA-214 contributes to regulation of necroptosis via targeting ATF4 in diabetes-associated periodontitis. 2019 Sep 1
42 31322207 Two novel 1,4‑naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species‑mediated MAPK/Akt/STAT3 signaling pathways. 2019 Sep 3
43 31322218 Antipsychotic agent pimozide promotes reversible proliferative suppression by inducing cellular quiescence in liver cancer. 2019 Sep 1
44 31345384 Expansion of PMN-myeloid derived suppressor cells and their clinical relevance in patients with oral squamous cell carcinoma. 2019 Aug 1
45 31360110 Enhancement of oxaliplatin-induced colon cancer cell apoptosis by alantolactone, a natural product inducer of ROS. 2019 1
46 31416122 Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of α-Synuclein. 2019 Aug 14 2
47 31432559 Quinalizarin induces cycle arrest and apoptosis via reactive oxygen species-mediated signaling pathways in human melanoma A375 cells. 2019 Dec 1
48 31499940 Thymoquinone loaded mesoporous silica nanoparticles retard cell invasion and enhance in vitro cytotoxicity due to ROS mediated apoptosis in HeLa and MCF-7 cell lines. 2019 Nov 2
49 28993239 Regulation of NADPH oxidase NOX4 by delta iodolactone (IL-δ) in thyroid cancer cells. 2018 Jul 15 1
50 29174637 Apolipoprotein E4 exacerbates ethanol-induced neurotoxicity through augmentation of oxidative stress and apoptosis in N2a-APP cells. 2018 Feb 5 2