Reactive Oxygen Species

BCL2 apoptosis regulator ; Homo sapiens







222 Article(s)
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1 34967073 CN-3 increases TMZ sensitivity and induces ROS-dependent apoptosis and autophagy in TMZ-resistance glioblastoma. 2022 Mar 1
2 35202708 Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H+] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes. 2022 Mar 15 1
3 35259676 Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway. 2022 May 1
4 35406117 Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. 2022 Apr 4 1
5 35409370 A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury. 2022 Apr 4 1
6 35422087 SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells. 2022 Apr 14 2
7 35620928 Design of Bio-Graphene-Based Multifunctional Nanocomposites Exhibits Intracellular Drug Delivery in Cervical Cancer Treatment. 2022 Jun 20 2
8 33262826 Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum. 2021 Jan 2
9 33470993 Cu(I) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action. 2021 Feb 9 2
10 33520087 Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis. 2021 1
11 33638996 Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter. 2021 Feb 26 1
12 33872672 Interactions between reactive oxygen species and autophagy: Special issue: Death mechanisms in cellular homeostasis. 2021 Jul 1
13 34064109 Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism. 2021 May 21 1
14 34242793 Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells. 2021 Aug 20 3
15 34290399 Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges. 2021 Aug 1
16 34302634 Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLARL downregulation in Caki-1 cells. 2021 Oct 1
17 34439474 Garcinia cambogia Ameliorates Non-Alcoholic Fatty Liver Disease by Inhibiting Oxidative Stress-Mediated Steatosis and Apoptosis through NRF2-ARE Activation. 2021 Jul 29 1
18 34492530 Photodynamic therapy of prostate cancer using porphyrinic formulations. 2021 Oct 2
19 34928029 An Efficient Carbon-Based Drug Delivery System for Cancer Therapy through the Nucleus Targeting and Mitochondria Mediated Apoptotic Pathway. 2021 Dec 2
20 31995555 Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. 2020 1
21 32103904 Hydrogen Sulfide Protects Against High Glucose-Induced Human Umbilical Vein Endothelial Cell Injury Through Activating PI3K/Akt/eNOS Pathway. 2020 1
22 32235588 Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation. 2020 Mar 30 1
23 32401088 CuS-NiS2 nanomaterials for MRI guided phototherapy of gastric carcinoma via triggering mitochondria-mediated apoptosis and MLKL/CAPG-mediated necroptosis. 2020 Aug 1
24 32560521 Isosamidin from Peucedanum japonicum Roots Prevents Methylglyoxal-Induced Glucotoxicity in Human Umbilical Vein Endothelial Cells via Suppression of ROS-Mediated Bax/Bcl-2. 2020 Jun 17 1
25 32745723 The balancing act of NEET proteins: Iron, ROS, calcium and metabolism. 2020 Nov 1
26 32827965 Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6. 2020 Dec 1 2
27 32878253 Interactions of Zinc Oxide Nanostructures with Mammalian Cells: Cytotoxicity and Photocatalytic Toxicity. 2020 Aug 31 2
28 33053856 GPR4 Knockout Improves the Neurotoxin-Induced, Caspase-Dependent Mitochondrial Apoptosis of the Dopaminergic Neuronal Cell. 2020 Oct 12 1
29 33099948 Anticancer activity of Voacangine against human oral cancer cells is due to G2/M cell cycle arrest, ROS-mediated cell death and inhibition of PI3K/AKT signalling pathway. 2020 Jul-Aug 1
30 33245769 Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism. 2020 Dec 16 5
31 30535477 Cryptotanshinone induces reactive oxygen species‑mediated apoptosis in human rheumatoid arthritis fibroblast‑like synoviocytes. 2019 Feb 1
32 30542709 Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway. 2019 Jan 3
33 30588027 Methotrexate-induced apoptosis in human ovarian adenocarcinoma SKOV-3 cells via ROS-mediated bax/bcl-2-cyt-c release cascading. 2019 1
34 31249651 Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway. 2019 6
35 29186971 Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison. 2018 Dec 1 1
36 29215703 Design, synthesis, and characterization of α, β-unsaturated carboxylic acid, and its urea based derivatives that explores novel epigenetic modulators in human non-small cell lung cancer A549 cell line. 2018 Jul 2
37 29217266 Auriculasin-induced ROS causes prostate cancer cell death via induction of apoptosis. 2018 Jan 2
38 29304561 Cross Talk Between Cellular Redox State and the Antiapoptotic Protein Bcl-2. 2018 Nov 1 1
39 29433671 Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells. 2018 Jan 15 1
40 29453988 Silencing calreticulin gene might protect cardiomyocytes from angiotensin II-induced apoptosis. 2018 Apr 1 1
41 29658330 Comparative cytotoxicity and apoptotic pathways induced by nanosilver in human liver HepG2 and L02 cells. 2018 Dec 1
42 29686591 Cytotoxicity and Genotoxicity of Cypermethrin in Hepatocarcinoma Cells: A Dose- and Time-Dependent Study. 2018 Apr-Jun 1
43 29725496 Melatonin Inhibits Reactive Oxygen Species-Driven Proliferation, Epithelial-Mesenchymal Transition, and Vasculogenic Mimicry in Oral Cancer. 2018 1
44 29786746 Luteolin induces myelodysplastic syndrome‑derived cell apoptosis via the p53‑dependent mitochondrial signaling pathway mediated by reactive oxygen species. 2018 Aug 3
45 29803995 Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2'-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs: Special exploration of their possible anticancer mechanism. 2018 Jun 25 1
46 29916532 Resveratrol induced reactive oxygen species and endoplasmic reticulum stress‑mediated apoptosis, and cell cycle arrest in the A375SM malignant melanoma cell line. 2018 Sep 3
47 29958912 Selective self-induced stimulus amplification prodrug platform for inhibiting multidrug resistance and lung metastasis. 2018 Aug 28 1
48 30542399 The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients. 2018 Dec 1
49 32254451 Mitochondrial dysfunction-induced apoptosis in breast carcinoma cells through a pH-dependent intracellular quercetin NDDS of PVPylated-TiO2NPs. 2018 Jun 7 2
50 33817118 Emodin Promotes Apoptosis of Human Endometrial Cancer Through Regulating the MAPK and PI3K/ AKT Pathways. 2018 Jan 2