Lapatinib


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496 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 1075
2 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 511
3 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 80
4 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 59
5 erb-b2 receptor tyrosine kinase 2 ERBB2_MOUSE Erbb2 Mus musculus 13866 567 48
6 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 23
7 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 23
8 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 22
9 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 21
10 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 21
11 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 18
12 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 18
13 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 17
14 nuclear receptor subfamily 4 group A member 1 NR4A1_HUMAN NR4A1 Homo sapiens 3164 657 15
15 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 15
16 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 14
17 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 14
18 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 14
19 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 12
20 epidermal growth factor receptor Q9QX70_RAT Egfr Rattus norvegicus 24329 495 11
21 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 11
22 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 9
23 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 9
24 major histocompatibility complex, class II, DR beta 1 DRB1_HUMAN HLA-DRB1 Homo sapiens 3123 402 9
25 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 9
26 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 8
27 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 8
28 LAP - LAP Homo sapiens 7939 377 8
29 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 8
30 erb-b2 receptor tyrosine kinase 4 ERBB4_HUMAN ERBB4 Homo sapiens 2066 169 8
31 neuregulin 1 NRG1_HUMAN NRG1 Homo sapiens 3084 229 7
32 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 7
33 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 7
34 interferon alpha inducible protein 27 IFI27_HUMAN IFI27 Homo sapiens 3429 662 7
35 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 7
36 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor MERL_HUMAN NF2 Homo sapiens 4771 212 7
37 erb-b2 receptor tyrosine kinase 3 ERBB3_MOUSE Erbb3 Mus musculus 13867 51 7
38 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 7
39 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 7
40 immunoglobulin heavy diversity 1-7 - IGHD1-7 Homo sapiens 28509 156 6
41 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 6
42 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 6
43 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 6
44 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 6
45 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 6
46 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 6
47 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 5
48 erb-b2 receptor tyrosine kinase 2 Q8K3F9_RAT Erbb2 Rattus norvegicus 24337 72 5
49 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 5
50 thymidylate synthetase TYSY_HUMAN TYMS Homo sapiens 7298 800 5