Protein Name forkhead box O3
Organism Homo sapiens
Gene ID 2309
Gene Symbol

FOXO3

UniProt O43524 (FOXO3_HUMAN)
Relationships Total Number of functionally related compound(s) : 544
Total Number of Articles : 850
Description

forkhead box O3

Gene Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

synonyms
  • forkhead box protein O3
  • FOXO3A-
  • forkhead box O3A
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Properties