Lapatinib

thymidylate synthetase ; Homo sapiens







5 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 29845287 Antitumor effect of lapatinib and cytotoxic agents by suppression of E2F1 in HER2‑positive breast cancer. 2018 Jul 2
2 25700774 Phase I Study of Lapatinib and Pemetrexed in the Second-Line Treatment of Advanced or Metastatic Non-Small-Cell Lung Cancer With Assessment of Circulating Cell Free Thymidylate Synthase RNA as a Potential Biomarker. 2015 Sep 1
3 21623901 Positive interaction between lapatinib and capecitabine in human breast cancer models: study of molecular determinants. 2012 Aug 3
4 20424000 Synergistic antitumor effect of S-1 and HER2-targeting agents in gastric cancer with HER2 amplification. 2010 May 1
5 19529774 Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2. 2009 Jun 16 5